Paraneoplastic Antibody Evaluation with Reflex to Titer and LB, Basic, CSF
Test code
CPT code(s)*
Test resources
Test FAQ
Details
Includes
Initial panel consists of: Paraneoplastic Antibody Screen, IFA
If the Paraneoplastic Ab Screen, IFA is positive for Aquaporin-4 Ab, IFA, then Aquaporin-4 (AQP4) Antibody (IgG), CBA, CSF will be performed at an additional charge (CPT code(s) 86052).
If Aquaporin-4 (AQP4) Antibody (IgG), CBA result is positive, then a titer will be performed at an additional charge (CPT code(s) 86052).
If the Paraneoplastic Ab Screen, IFA is positive for ANNA3 Ab IFA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If the Paraneoplastic Ab Screen, IFA is positive for PCA2 Ab IFA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If the Paraneoplastic Ab Screen, IFA is indeterminate or positive for ANNA1, ANNA2, PCA1, PCA-Tr (DNER), Amphiphysin, GAD65, or CRMP5 (CV2) antibodies, then Paraneoplastic Antibody, Line Blot will be performed.
If the Paraneoplastic Ab Screen, IFA is positive for NMDAR1, LGI-1, CASPR2, AMPAR1, AMPAR2, GABA receptor B, or Voltage Gated Antibodies, then Paraneoplastic Antibody, CBA IFA will be performed.
If Paraneoplastic Antibody, CBA IFA is positive for NMDAR1 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA IFA is positive for AMPAR1 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA, IFA is positive for AMPAR2 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA IFA is positive for GABA receptor B Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA IFA is positive for LGI-1 Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA IFA is positive for CASPR2 Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If the Paraneoplastic Ab Screen, IFA is positive for LGI-1, CASPR2, or Voltage Gated Antibodies, then Voltage-Gated Potassium Channel (VGKC) Antibody, CSF will be performed at an additional charge (CPT code(s) 83519).
Assay category
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Alternative name(s)
Brain antibody,Anti-neuronal antibody
Specimen requirements | |
|---|---|
| Patient preparation | None Specified |
| Preferred specimen(s) | 3 mL CSF collected in a sterile leak-proof container |
| Minimum volume | 1.5 mL |
| Transport container | Sterile leak-proof container |
| Transport temperature | Refrigerated (cold packs) |
| Specimen stability | Room temperature: 48 hours Refrigerated: 14 days Frozen: 21 days |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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