Advanced Lipid Panel with Inflammation, Cardio IQ®

Advanced Lipid Panel with Inflammation, Cardio IQ®

Test Code

94220
80061, 83704, 82172, 83695, 86141, 83698
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
94220
80061, 83704, 82172, 83695, 86141, 83698
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano | Quest Nichols Institute -San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Advanced Lipid Panel with Inflammation, Cardio IQ® - The 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults recommend matching the intensity of statin treatment with the absolute risk of cardiovascular events. However, the standard lipid panel alone does not provide a complete assessment of absolute risk of CVD. Adding advanced CVD markers (ion mobility, apob, lp(a), hs crp and lppla2) in addition to the lipid panel will improve assessment of the CVD risk.

Test Resources

Test FAQ

Cardio IQ Lipoprotein Fractionation, Ion Mobility

Test Details

Includes

  • Cardio IQ® Cholesterol, Total
  • Cardio IQ® HDL Cholesterol
  • Cardio IQ® Triglycerides
  • Cardio IQ® Non-HDL and Calculated Components
  • Cardio IQ® Lipoprotein Fractionation, Ion Mobility
  • Cardio IQ® Apolipoprotein B
  • Cardio IQ® Lipoprotein (a)
  • Cardio IQ® hs-CRP
  • Cardio IQ® Lp-PLA2 Activity
  •  
  • If Triglyceride is >400 mg/dL, then Cardio IQ® Direct LDL will be performed at an additional charge (CPT code(s): 83721).

Patient Preparation

If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 0-12 hours prior to collection. If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required.

Methodology

Enzymatic • Immunoassay (IA) • Immunoturbidimetric Assay • Ion Mobility • Nephelometry • Spectrophotometry (SP)

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See Laboratory Report

Alternative Name(s)

CardioIQ®,Cardio IQ® Advanced Lipid Panel and Inflammation Panel

LOINC® Codes, Performing Laboratory

Service Area must be determined
Cardio IQ® Cholesterol, Total
Cardio IQ® HDL Cholesterol
Cardio IQ® Triglycerides
Cardio IQ® Non-HDL and Calculated Components
Cardio IQ® Lipoprotein Fractionation, Ion Mobility
Cardio IQ® Apolipoprotein B
Cardio IQ® Lipoprotein (a)
Cardio IQ® hs-CRP
Cardio IQ® Lp-PLA2 Activity

If Triglyceride is >400 mg/dL, then Cardio IQ® Direct LDL will be performed at an additional charge (CPT code(s): 83721).

If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 0-12 hours prior to collection. If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required.

Methodology

Enzymatic • Immunoassay (IA) • Immunoturbidimetric Assay • Ion Mobility • Nephelometry • Spectrophotometry (SP)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See Laboratory Report

Alternative Name(s)

CardioIQ®,Cardio IQ® Advanced Lipid Panel and Inflammation Panel
Service Area must be determined

Preferred Specimen(s)

6 mL serum

Minimum Volume

3 mL

Collection Instructions

The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for...Cholesterol, Uric Acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hr, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 24 hours
    Refrigerated: 7 days
    Frozen: 28 days

Reject Criteria

Hemolysis • Moderate to grossly lipemic • Icteric

Setup Schedule

Service Area must be determined
6 mL serum

3 mL

The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for...Cholesterol, Uric Acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hr, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.
Transport tube
Refrigerated (cold packs)
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days
Hemolysis • Moderate to grossly lipemic • Icteric
Service Area must be determined
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano | Quest Nichols Institute -San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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