Cardio IQ® Lp-PLA2 Activity

Cardio IQ® Lp-PLA2 Activity

Test Code

94218
83698
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
94218
83698
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano | Quest Nichols Institute -San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Cardio IQ® Lp-PLA2 Activity - Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet activating factor Acetylhydrolase, is an inflammatory enzyme that circulates bound mainly to low density lipoproteins and has been found to be localized and enriched in atherosclerotic plaques. In multiple clinical trials, Lp-PLA2 activity has been shown to be an independent predictor of coronary heart disease and stroke in the general population. Measurement of Lp-PLA2 may be used along with traditional cardiovascular risk factor measures for identifying individuals at higher risk of cardiovascular disease events. Clinical ...

Test Resources

None found for this test
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Test Details

Patient Preparation

Fasting preferred, but not required

Methodology

Enzymatic Assay (EZA)

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Risk

Optimal ≤123 nmol/min/mL
High >123 nmol/min/mL

Alternative Name(s)

CardioIQ®, PAF-AH

LOINC® Codes, Performing Laboratory

Service Area must be determined
Fasting preferred, but not required

Methodology

Enzymatic Assay (EZA)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Risk
Optimal ≤123 nmol/min/mL
High >123 nmol/min/mL

Alternative Name(s)

CardioIQ®, PAF-AH
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Collection Instructions

Process samples by removing or separating serum from red blood cells using standard separation procedures. Recommend to centrifuge and separate samples within four hours of venipuncture as per good laboratory practices.

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 28 days
  • Refrigerated: 28 days
  • Frozen: 90 days

Reject Criteria

Hemolysis • Moderate to grossly lipemic • Moderate to grossly icteric

Setup Schedule

Service Area must be determined
1 mL serum
0.5 mL
Process samples by removing or separating serum from red blood cells using standard separation procedures. Recommend to centrifuge and separate samples within four hours of venipuncture as per good laboratory practices.
Transport tube
Refrigerated (cold packs)
Room temperature: 28 days
Refrigerated: 28 days
Frozen: 90 days
Hemolysis • Moderate to grossly lipemic • Moderate to grossly icteric
Service Area must be determined
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano | Quest Nichols Institute -San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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