Aquaporin-4 Antibody (IgG), CBA
Test Code
93893
86052
In-home collection is not available in your area through Quest Mobile.
Clinical Significance
Aquaporin-4 Antibody (IgG), CBA - Antibody to Aquaporin 4 causes neuromyelitis optica (NMO), a demyelinating disease of the central nervous system often confused diagnostically with multiple sclerosis (MS) and/or transverse myelitis. NMO causes optic neuritis and transverse myelitis. Early discrimination between MS and NMO is important, as optimum treatment for both diseases may differ considerably.
Test Resources
Test Details
Methodology
Cell Binding Assay-Immunofluorescence Assay
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
Negative
Preferred Specimen(s)
0.5 mL serum collected in a red-top tube (no gel) or CSF collected in a sterile, screw-cap container
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 21 days
Reject Criteria
Serum separator tube (SST)
Setup Schedule
0.5 mL serum collected in a red-top tube (no gel) or CSF collected in a sterile, screw-cap container
0.3 mL
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Serum separator tube (SST)