Voltage-Gated Calcium Channel (VGCC) Type N Antibody

Voltage-Gated Calcium Channel (VGCC) Type N Antibody

Test Code

93882
86596
93882
86596
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Voltage-Gated Calcium Channel (VGCC) Type N Antibody - N-type calcium channel antibodies are more highly associated with primary lung cancer than P/Q-type. One or all of the autoantibodies in the myasthenia gravis (MG)/LEMS evaluation can occur with neoplasia without evidence of neurological impairment. One or both calcium channel antibodies (P/Q and N) can occur with paraneoplastic and idiopathic cerebellar ataxia, encephalomyeloneuropathies, and autonomic neuropathy. Classical symptoms of LEMS include proximal muscle weakness, fatigability, dry mouth and impotence. When presentation is further complicated with oculobulbar weakness, these symptoms ...

Test Resources

Algorithm

Selection of Antibody Tests in the Confirmation and Assessment of Suspected Generalized Myasthenia Gravis

Clinical Focus

Myasthenia Gravis and Autoantibodies

Clinical Focus

Paraneoplastic Neurological Syndromes: Laboratory Support of Diagnosis

Test Details

Methodology

Radioimmunoassay (RIA)

Reference Range(s)

<54 pmol/L

Alternative Name(s)

N-VGCC, NCC

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Radioimmunoassay (RIA)

Reference Range(s)

<54 pmol/L

Alternative Name(s)

N-VGCC, NCC
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: 48 hours
  • Refrigerated: 48 hours
  • Frozen: 60 days

Setup Schedule

Service Area must be determined
1 mL serum
0.5 mL
Transport tube
Frozen
Room temperature: 48 hours
Refrigerated: 48 hours
Frozen: 60 days
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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