Paraneoplastic Antibody Evaluation w/Reflex to Titer and Line Blot,Basic
Test code
CPT code(s)*
Clinical significance
Test resources
Test FAQ
Details
Includes
Initial panel consists of:
Paraneoplastic Antibody Screen IFA Basic
Striated Muscle Antibody with Reflex to Titer
Acetylcholine Receptor Binding Antibody
Acetylcholine Receptor Ganglionic (Alpha 3) Antibody
Voltage-Gated Calcium Channel (VGCC) Type N Antibody
Voltage-Gated Calcium Channel (VGCC) Type P/Q Antibody
Voltage-Gated Potassium Channel (VGKC) Antibody
If Paraneoplastic Antibody Screen, IFA, Basic is positive for ANNA3, then ANNA-3 Ab, IFA Titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody Screen, IFA, Basic is positive for PCA-2, then PCA-2 Ab, IFA Titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody Screen, IFA, Basic suggests NMO-5-IgG, then specific CBA-IFA assay will be performed at an additional charge (CPT code(s) 86255).
If Paraneoplastic Antibody Screen, IFA, Basic suggests AMPA-R, GABA-B-R, or NMDA-R, then specific CBA-IFA assay will be performed.
If Paraneoplastic Antibody Screen, IFA, Basic is positive or indeterminate, then Paraneoplastic Antibody, LB, Basic will be performed.
If Striated Muscle Antibody Screen is positive, then Striated Muscle Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
If Acetylcholine Receptor Binding Antibody is positive (≥0.50) or equivocal (0.31-0.49), then Paraneoplastic Antibody, LB, Basic and Acetylcholine Receptor Modulating Antibody will both be performed at additional charges (CPT code(s) 86043).
Methodology
See individual tests
Assay category
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Specimen requirements | |
|---|---|
| Patient preparation | None Specified |
| Preferred specimen(s) | 6 mL frozen serum |
| Minimum volume | 3 mL |
| Transport container | Transport tube |
| Transport temperature | Refrigerated (cold packs) |
| Specimen stability | Room temperature: 48 hours Refrigerated: 14 days Frozen 21 days |
| Reject criteria | Gross hemolysis • Grossly lipemic |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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