Hepatitis C Viral RNA Genotype 3 NS5a Drug Resistance

Test Code

93325

CPT Code(s)

87902

Test Code

93325

CPT Code(s)

87902

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Hepatitis C Viral RNA Genotype 3 NS5a Drug Resistance - For detection of mutations in the genotype 3 NS5a gene associated with resistance to NS5a inhibitors (example: daclatasvir, velpatasvir) including the Y93H polymorphism.

Test Resources

Test FAQ

Hepatitis C Viral RNA Genotype 3 NS5A Drug Resistance

Clinical Focus

Viral Hepatitis: Laboratory Support for Diagnosis and Management

Test Details

Includes

HCV NS5a Subtype, Daclatasvir Resistance, Velpatasvir Resistance

Methodology

Polymerase Chain Reaction (PCR) • Sequencing

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See Laboratory Report

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

HCV NS5a Subtype, Daclatasvir Resistance, Velpatasvir Resistance

Methodology

Polymerase Chain Reaction (PCR) • Sequencing

Assay Category

Reference Range(s)

See Laboratory Report

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

2 mL plasma collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

Plasma collected in: PPT potassium EDTA (white-top) tube • Serum

Minimum Volume

0.6 mL

Collection Instructions

Separate plasma from whole blood within 24 hours of collection by centrifugation. Transfer to a transport tube and refrigerate or freeze.

Serum is collected in a serum separator tube (SST) or red-top tube (no gel). Transfer to a transport tube and refrigerate or freeze.

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 42 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Specimens using heparin as the anticoagulant

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

2 mL plasma collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

Plasma collected in: PPT potassium EDTA (white-top) tube • Serum

Minimum Volume

0.6 mL

Collection Instructions

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 42 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Specimens using heparin as the anticoagulant

Setup Schedule

Service Area must be determined

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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