HPV Genotypes 16, 18/45, Anal-Rectal

HPV Genotypes 16, 18/45, Anal-Rectal

Test Code

92807
87625
92807
87625
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

HPV Genotypes 16, 18/45, Anal-Rectal - Assay is used in combination with anal and rectal cytology to assess the presence or absence of high-risk HPV genotypes 16, 18, and/or 45. This information together with physician's assessment of cytology history, other risk factors and professional guidelines, may be used to guide patient management.

Test Resources

None found for this test
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Test Details

Methodology

Transcription-Mediated Amplification (TMA)

Assay Category

The analytical performance characteristics of this assay have been determined by Quest Diagnostics. The modifications have not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Not Detected

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Transcription-Mediated Amplification (TMA)
The analytical performance characteristics of this assay have been determined by Quest Diagnostics. The modifications have not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Not Detected
Service Area must be determined

Preferred Specimen(s)

Anal/rectal specimen collected using a dacron/polyester swab or anal/rectal brush and submitted in 3 mL Preservcyt® transport medium ThinPrep® vial or Aptima® specimen transfer tube (green label)

Minimum Volume

1.5 mL

Collection Instructions

To collect an anal-rectal sample, a wetted, non-lubricated Dacron/Polyester swab is used. The Dacron/Polyester swab is inserted about 3 cm (or until resistance is met) into the anal canal past the anal verge, into the rectal vault. This is done without visualization of the anal canal. Firm lateral pressure is applied to the swab handle as it is rotated and slowly moved in and out. Slowly withdraw swab from the anal canal. Swish the swab vigorously in PreservCyt® fluid in the ThinPrep® vial. Discard the swab. Cap and tighten the ThinPrep® vial.
Follow the same procedure if using a brush to collect an anal-rectal sample. Avoid using cotton swab on a wooden stick because the handle may break and splinter during collection. Swab that is grossly contaminated with feces should be discarded and the collection repeated.

Transport Container

Liquid Cytology (PreservCyt®) Preservative (ThinPrep®) vial

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 30 days
    Refrigerated: 30 days
    Frozen: Not established

Setup Schedule

Service Area must be determined
Anal/rectal specimen collected using a dacron/polyester swab or anal/rectal brush and submitted in 3 mL Preservcyt® transport medium ThinPrep® vial or Aptima® specimen transfer tube (green label)
1.5 mL
To collect an anal-rectal sample, a wetted, non-lubricated Dacron/Polyester swab is used. The Dacron/Polyester swab is inserted about 3 cm (or until resistance is met) into the anal canal past the anal verge, into the rectal vault. This is done without visualization of the anal canal. Firm lateral pressure is applied to the swab handle as it is rotated and slowly moved in and out. Slowly withdraw swab from the anal canal. Swish the swab vigorously in PreservCyt® fluid in the ThinPrep® vial. Discard the swab. Cap and tighten the ThinPrep® vial.
Follow the same procedure if using a brush to collect an anal-rectal sample. Avoid using cotton swab on a wooden stick because the handle may break and splinter during collection. Swab that is grossly contaminated with feces should be discarded and the collection repeated.
Liquid Cytology (PreservCyt®) Preservative (ThinPrep®) vial
Room temperature
Room temperature: 30 days
Refrigerated: 30 days
Frozen: Not established
Service Area must be determined
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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