QNatal® Advanced

Test Code

92777

CPT Code(s)

81420

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Test Code

92777

CPT Code(s)

81420

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

QNatal® Advanced - QNatal® Advanced is a cell-free DNA test that screens for increased risk of certain fetal chromosomal abnormalities that may cause birth defects, including Trisomy 21 (Down Syndrome), Trisomy 18 (Edwards Syndrome), Trisomy 13 (Patau Syndrome) and certain sex chromosome abnormalities (i.e., 45,X, 47,XXY, 47,XXX, and 47,XYY). In addition, if selected as an option, QNatal Advanced can screen for certain microdeletions (i.e., 22q, 5p, 1p36, 15q, 11q, 8q, and 4p) that may cause birth defects, and/or for fetal sex.

This test does not assess the risk of fetal anomalies such as neural tube defects ...

Test Resources

Test FAQ

QNatal Advanced

Test Details

Methodology

Next Generation Sequencing

Assay Category

QNatal Advanced is a laboratory developed test that has been developed and validated, pursuant to the Clinical Laboratory Improvements Amendments of 1988 (CLIA), and as such it has not been reviewed by FDA.

Reference Range(s)

See Laboratory Report

Alternative Name(s)

NIPT

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Next Generation Sequencing

Assay Category

Reference Range(s)

See Laboratory Report

Alternative Name(s)

NIPT

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

10 mL whole blood collected in a Streck cell-free (black/tan tiger-top) glass tube

Minimum Volume

8 mL

Collection Instructions

Do not draw before 10 weeks gestation. Sample collection using a straight needle (not a butterfly needle) is preferred. Use Streck tubes only.

Transport Container

Cell-free DNA Streck tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerate: Unacceptable
Frozen: Unacceptable

Reject Criteria

Whole blood collected in other than Streck tube

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

10 mL whole blood collected in a Streck cell-free (black/tan tiger-top) glass tube

Minimum Volume

8 mL

Collection Instructions

Do not draw before 10 weeks gestation. Sample collection using a straight needle (not a butterfly needle) is preferred. Use Streck tubes only.

Transport Container

Cell-free DNA Streck tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerate: Unacceptable
Frozen: Unacceptable

Reject Criteria

Whole blood collected in other than Streck tube

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.