F2-Isoprostane/Creatinine Ratio
Test Code
Clinical Significance
F2-Isoprostane/Creatinine Ratio - The F2-isoprostane/creatinine ratio is the "gold standard" for measuring oxidative stress and has utility in individuals who have lifestyle risks due to poor diet or smoking, a family history of cardiovascular disease, or hyperlipidemia. High levels are seen in conditions associated with increased risk of atherosclerosis and certain cancers.
Test Resources
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Test Details
Methodology
Cardiometabolic Center of Excellence at Cleveland HeartLab. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
Alternative Name(s)
Preferred Specimen(s)
2 mL random urine collected in a preservative-free urine collection container (cup)
Minimum Volume
1.5 mL
Collection Instructions
1. Collect urine sample in a preservative-free urine collection container (cup) according to standard protocols.
2. Transfer aliquot into a preservative-free urine specimen tube using the vacutainer transfer device included with the tube.
3. Label urine specimen tube according to standard protocols. Store and transport refrigerated. Discard urine collection container (cup).
Transport Container
Preservative-free urine collection container
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria
Specimens other than preservative-free urine
Setup Schedule
2. Transfer aliquot into a preservative-free urine specimen tube using the vacutainer transfer device included with the tube.
3. Label urine specimen tube according to standard protocols. Store and transport refrigerated. Discard urine collection container (cup).
Refrigerated: 7 days
Frozen: 28 days