Liver Fibrosis, FibroTest-ActiTest Panel

Liver Fibrosis, FibroTest-ActiTest Panel

Test Code

92688
81596
92688
81596
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Liver Fibrosis, FibroTest-ActiTest Panel - FibroTest and ActiTest permit the non-invasive evaluation of Hepatitis C (or B) individuals for the presence of liver fibrosis and liver inflammation, respectively. The FibroTest and ActiTest scores are calculated based on patient age, gender and concentrations of serum of y-glutamyl transferase (GGT), total bilirubin (TB), a-2 macroglobulin, haptoglobin, apolipoprotein A1 and alanine aminotransferase (ActiTest). Fibrotest and ActiTest Scores, on a scale of 0.0 to 1.0, are assigned a Metavir scale indicating the level of fibrosis or inflammation present.

Test Resources

Clinical Focus

Viral Hepatitis: Laboratory Support for Diagnosis and Management

Test Details

Includes

  • Fibrosis Score, Fibrosis Stage, Fibrosis Interpretation
  • Necroinflammat Act Score, Necroinflammat Act Grade, Necroinflammat Interpretation
  • Alpha-2-Macroglobulin
  • Haptoglobin
  • Apolipoprotein A1
  • Total Bilirubin
  • GGT
  • ALT

Patient Preparation

Overnight fasting is preferred

Methodology

Nephelometry • Spectrophotometry (SP)

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See Laboratory Report

LOINC® Codes, Performing Laboratory

Service Area must be determined
Fibrosis Score, Fibrosis Stage, Fibrosis Interpretation
Necroinflammat Act Score, Necroinflammat Act Grade, Necroinflammat Interpretation
Alpha-2-Macroglobulin
Haptoglobin
Apolipoprotein A1
Total Bilirubin
GGT
ALT
Overnight fasting is preferred

Methodology

Nephelometry • Spectrophotometry (SP)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See Laboratory Report
Service Area must be determined

Preferred Specimen(s)

3.5 mL serum

Minimum Volume

2 mL

Collection Instructions

Serum should be separated from the cells as soon as possible after visible clot formation (usually 15-30 minutes after collection). Avoid freezing and thawing.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: 24 hours
    Refrigerated: 72 hours
    Frozen -20° C: 5 days
    Frozen -70° C: 28 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Patients <2 years old • QNS for one or more analytes

Setup Schedule

Service Area must be determined
3.5 mL serum
2 mL
Serum should be separated from the cells as soon as possible after visible clot formation (usually 15-30 minutes after collection). Avoid freezing and thawing.
Transport tube
Frozen
Room temperature: 24 hours
Refrigerated: 72 hours
Frozen -20° C: 5 days
Frozen -70° C: 28 days
Gross hemolysis • Grossly lipemic • Patients <2 years old • QNS for one or more analytes
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.

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