FISH, Myeloma, Chromosomes CEP 9, 11, 15
Test Code
92495
88271(x3), 88275
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Clinical Significance
FISH, Myeloma, Chromosomes CEP 9, 11, 15 - Plasma Cell Myeloma (PCM) is characterized by the proliferation of malignant monoclonal plasma cells in the bone marrow. Hyperdiploidy with gains of odd numbered chromosomes, including 9, 11, and 15, has been associated with a more favorable outcome in myeloma patients. This test replaces FISH, Multiple Myeloma (5, 9, 15), which is no longer available.
Test Resources
None found for this test
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Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Test Details
Methodology
Fluorescence in situ Hybridization (FISH)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
See Laboratory Report
Preferred Specimen(s)
3 mL bone marrow collected in a sodium heparin (green-top) tube
Alternative Specimen(s)
Sodium heparin (royal blue-top) tube • Sodium heparin lead-free (tan-top) tube
Minimum Volume
1 mL
Transport Container
Sodium heparin (green-top) tube
Transport Temperature
Room temperature
Specimen Stability
- Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not Reject.
Setup Schedule
3 mL bone marrow collected in a sodium heparin (green-top) tube
Sodium heparin (royal blue-top) tube • Sodium heparin lead-free (tan-top) tube
1 mL
Sodium heparin (green-top) tube
Room temperature
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not Reject.