Substance P
Test Code
Clinical Significance
Substance P - Substance P is a neuropeptide present in the central and peripheral nervous system. Substance P is a neurotransmitter released in response to pain and other noxious stimuli. Substance P is a neuropeptide of the tachykinin class that also includes neurokinin. Substance P is found in the brain, spinal cored, and peripheral tissues and is released from nerve endings in response to stimuli. Increased substance P levels can occur in neurogenic inflammation and physiological stress and may be associated with cardinoid or neuroendocrine tumors.
Test Resources
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Test Details
Methodology
Enzyme Immunoassay (EIA)
This test is not available for New York patient testing.
Reference Range(s)
Preferred Specimen(s)
5 mL serum
Minimum Volume
1 mL
Collection Instructions
Serum: collect blood in SST tube. Allow to clot for 30 min at room temperature. Centrifuge sample at 1000 X G for 15 minutes. Separate serum into a transfer tube as soon as possible. Freeze at -20° C immediately.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: None
- Refrigerated: None
- Frozen: 30 days
Reject Criteria
Received unfrozen • Received room temperature • Specimens outside of listed stability • Plasma
Setup Schedule
Refrigerated: None
Frozen: 30 days