ASCVD Risk Panel with Score

ASCVD Risk Panel with Score

Test Code

92053
80061
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
92053
80061
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

ASCVD Risk Panel with Score - This panel provides the 10-year and lifetime risk of atherosclerotic cardiovascular disease (ASCVD) using lipid results with anthropomorphic data and family history.
The ASCVD risk assessment is recommended in the 2013 ACC/AHA Guidelines on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults.

Test Details

Includes

  • Cholesterol, Total
    Triglycerides
    HDL Cholesterol
    LDL-Cholesterol (calculated)
    Cholesterol/HDL Ratio (calculated)
    Non-HDL Cholesterol (calculated)
    ASCVD Risk Scores

    If Triglyceride is >400 mg/dL, Direct LDL will be performed at an additional charge (CPT code(s): 83721).

Patient Preparation

If a cholesterol measurement is to be performed along with triglycerides, the patient should be fasting 9-12 hours prior to collection. The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been. . . determined to interfere with assays for. . . cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.

Methodology

Enzymatic • Spectrophotometry (SP)

Reference Range(s)


Total Cholesterol
Male 
(mg/dL)
Female 
(mg/dL)
<20 Years<170<170
≥20 Years<200<200
HDL Cholesterol  
<20 Years>45>45
≥20 Years≥40≥50
Triglycerides  
≤9 Years<75<75
10-19 Years<90<90
≥20 Years<150<150
  
LDL-Cholesterol (Calc)  
<20 Years<110<110
≥20 Years<100<100
Cholesterol/HDL Ratio (Calc)<5.0<5.0
Non-HDL Cholesterol  
<20 Years<120<120
≥20 Years<130<130
⁠⁠⁠⁠⁠⁠⁠
ASCVD Risk ScoresSee Laboratory Report

LOINC® Codes, Performing Laboratory

Cholesterol, Total
Triglycerides
HDL Cholesterol
LDL-Cholesterol (calculated)
Cholesterol/HDL Ratio (calculated)
Non-HDL Cholesterol (calculated)
ASCVD Risk Scores

If Triglyceride is >400 mg/dL, Direct LDL will be performed at an additional charge (CPT code(s): 83721).
If a cholesterol measurement is to be performed along with triglycerides, the patient should be fasting 9-12 hours prior to collection. The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been. . . determined to interfere with assays for. . . cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.

Methodology

Enzymatic • Spectrophotometry (SP)

Reference Range(s)


Total Cholesterol
Male 
(mg/dL)
Female 
(mg/dL)
<20 Years<170<170
≥20 Years<200<200
HDL Cholesterol  
<20 Years>45>45
≥20 Years≥40≥50
Triglycerides  
≤9 Years<75<75
10-19 Years<90<90
≥20 Years<150<150
  
LDL-Cholesterol (Calc)  
<20 Years<110<110
≥20 Years<100<100
Cholesterol/HDL Ratio (Calc)<5.0<5.0
Non-HDL Cholesterol  
<20 Years<120<120
≥20 Years<130<130
⁠⁠⁠⁠⁠⁠⁠
ASCVD Risk ScoresSee Laboratory Report

Preferred Specimen(s)

2 mL serum

Minimum Volume

1 mL

Collection Instructions

For risk calculations to be performed, the following patient specific information have to be provided at time of order:
Age: Years
Gender: M (for male) or F (for female)
Race-African American: Y (for yes) or N (for no)
Systolic Blood Pressure: mmHg
Treatment for High Blood Pressure: Y (for yes) or N (for no)
Diabetes Status: Y (for yes) or N (for no)
Smoking Status: Y (for Yes) or N (for no)

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 48 hours
  • Refrigerated: 7 days
  • Frozen: 28 days

Reject Criteria

Gross hemolysis • Moderate to gross icterus • Anticoagulants other than heparin

Setup Schedule

2 mL serum
1 mL
For risk calculations to be performed, the following patient specific information have to be provided at time of order:
Age: Years
Gender: M (for male) or F (for female)
Race-African American: Y (for yes) or N (for no)
Systolic Blood Pressure: mmHg
Treatment for High Blood Pressure: Y (for yes) or N (for no)
Diabetes Status: Y (for yes) or N (for no)
Smoking Status: Y (for Yes) or N (for no)
Transport tube
Room temperature
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 28 days
Gross hemolysis • Moderate to gross icterus • Anticoagulants other than heparin
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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