Interleukin 8 | Test Detail | Quest Diagnostics

Interleukin 8

Test Code

91833

CPT Code(s)

83520

Test Code

91833

CPT Code(s)

83520

Ordering Restrictions may apply. Please provide SERVICE AREA INFORMATION to find available tests you can order.

This test is not available in all locations. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Interleukin 8 - The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 8 is a 6,000-8000 molecular weight glycoprotein produced primarily by macrophages and monocytes. Its primary target cells are neutrophils. Interleukin 8 is a chemotactic agent for monocytes and neutrophils. Interleukin 8 causes oxygen radical and enzyme release by neutrophils and mobilizes products into circulation. Interleukin 8 is stimulated by Interleukin 1 and Tumor Necrosis Factor.

Test Resources

None found for this test
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Test Details

Patient Preparation

Patient should not be on any corticosteroids, anti-inflammatory medications or pain killers, if possible, for at least 48 hours prior to collection of specimen.

Methodology

Enzyme Immunoassay (EIA)

Assay Category

This test was developed and its performance characteristics have been determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.

This test is not available for New York patient testing.

Reference Range(s)

Plasma	Up to 22.6 pg/mL
Serum	Up to 35.0 pg/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Patient Preparation

Patient should not be on any corticosteroids, anti-inflammatory medications or pain killers, if possible, for at least 48 hours prior to collection of specimen.

Methodology

Enzyme Immunoassay (EIA)

Assay Category

This test is not available for New York patient testing.

Reference Range(s)

Plasma	Up to 22.6 pg/mL
Serum	Up to 35.0 pg/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

3 mL serum

Alternative Specimen(s)

Plasma collected in an EDTA (lavender-top) tube

Minimum Volume

1 mL

Collection Instructions

Specimen should be separated as soon as possible. Freeze immediately after separation.

Special Specimens: For tumor/tissue and various fluids (i.e. CSF, peritoneal, synovial, etc.) contact the Institute for requirements and special handling.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 24 hours
frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric • Received room temperature • Received refrigerated

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

3 mL serum

Alternative Specimen(s)

Plasma collected in an EDTA (lavender-top) tube

Minimum Volume

1 mL

Collection Instructions

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 24 hours
frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric • Received room temperature • Received refrigerated

Setup Schedule

Service Area must be determined

Ordering Restrictions may apply. Please provide SERVICE AREA INFORMATION to find available tests you can order.

This test is not available in all locations. Please provide ACCOUNT INFORMATION NEEDED to confirm Test Code for the lab that services your account or to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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