Prostate Triple Stain (P504S, HMW Keratins, P63), IHC with Interpretation

Prostate Triple Stain (P504S, HMW Keratins, P63), IHC with Interpretation

Test Code

91478
88344
91478
88344
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Prostate Triple Stain (P504S, HMW Keratins, P63), IHC with Interpretation - Pathologic evaluation of prostate cancer can be challenging, especially when there is a small focus of cancer. Because benign prostate glands contain basal cells, while cancerous glands do not, differential staining of basal cells in the prostate may be useful for diagnosis. This test uses a combination of several antibodies (applied to a single slide) that differentially stain for basal cells and neoplastic cells in the prostate: P504S stains prostate adenocarcinoma, whereas p63 and the high molecular weight cytokeratins stain benign prostate basal epithelial tissue. This combination may help ...

Test Resources

None found for this test
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Test Details

Methodology

Immunohistochemistry (IHC)

Reference Range(s)

See Laboratory Report

Alternative Name(s)

CK14,P504S,Prostate Cancer,CK5,34betaE12,K903,p63,PIN-4

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunohistochemistry (IHC)

Reference Range(s)

See Laboratory Report

Alternative Name(s)

CK14,P504S,Prostate Cancer,CK5,34betaE12,K903,p63,PIN-4
Service Area must be determined

Preferred Specimen(s)

Formalin-fixed, paraffin-embedded tissue

Alternative Specimen(s)

5 unstained, positively charged slides submitted in IHC specimen transport kit

Collection Instructions

Include Surgical Pathology Report

Transport Container

IHC specimen transport kit

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: Indefinite
  • Refrigerated: Indefinite
  • Frozen: Unacceptable

Reject Criteria

Received frozen

Setup Schedule

Service Area must be determined
Formalin-fixed, paraffin-embedded tissue
5 unstained, positively charged slides submitted in IHC specimen transport kit
Include Surgical Pathology Report
IHC specimen transport kit
Room temperature
Room temperature: Indefinite
Refrigerated: Indefinite
Frozen: Unacceptable
Received frozen
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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