Rheumatoid Arthritis Diagnostic Panel 2

Rheumatoid Arthritis Diagnostic Panel 2

Test Code

91472
86431, 86200, 83520
91472
86431, 86200, 83520
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Rheumatoid Arthritis Diagnostic Panel 2 - Autoantibody testing has a major role in the diagnosis of RA. This panel includes Rheumatoid factor (RF), anti-cyclic citrullinated peptide (CCP) and anti-mutated citrullinated vimentin (MCV). RF is found in a majority of patients with RA but is not specific for the diagnosis. Anti-CCP antibody is more sensitive and highly specific. RF and anti-CCP are included in the most recent classification criteria for RA. The past several years have seen a search for biomarkers which might increase sensitivity in order to identify the minority of RA patients who are negative for either RF or CCP, especially ...

Test Resources

Algorithm

ANA, IFA, Cascade with Rheumatoid Arthritis Panel 2, with Reflexes (test code 94954).

Clinical Focus

Autoimmune Rheumatic and Related Diseases

Test Summary

ANA, IFA, Cascade and Rheumatoid Arthritis Panel 2, With Reflexes

Test Details

Includes

  • Rheumatoid Factor
    Cyclic Citrullinated Peptide (CCP) Antibody (IgG)
    Mutated Citrullinated Vimentin (MCV) Antibody

Methodology

Enzyme Linked Immunosorbent Immunoassay (ELISA) • Immunoturbidimetric Assay

Reference Range(s)

Rheumatoid Factor<14 IU/mL

CCP Antibody (IgG) 
  Negative<20 units
  Weak positive20-39 units
  Moderate positive40-59 units
  Strong positive>59 units

MCV Antibody<20 U/mL

Alternative Name(s)

Rheumatoid Factor

LOINC® Codes, Performing Laboratory

Service Area must be determined
Rheumatoid Factor
Cyclic Citrullinated Peptide (CCP) Antibody (IgG)
Mutated Citrullinated Vimentin (MCV) Antibody

Methodology

Enzyme Linked Immunosorbent Immunoassay (ELISA) • Immunoturbidimetric Assay

Reference Range(s)

Rheumatoid Factor<14 IU/mL

CCP Antibody (IgG) 
  Negative<20 units
  Weak positive20-39 units
  Moderate positive40-59 units
  Strong positive>59 units

MCV Antibody<20 U/mL

Alternative Name(s)

Rheumatoid Factor
Service Area must be determined

Preferred Specimen(s)

3 mL serum

Minimum Volume

1.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 4 days
  • Refrigerated: 7 days
  • Frozen: 21 days

Reject Criteria

See individual tests

Setup Schedule

Service Area must be determined
3 mL serum
1.5 mL
Transport tube
Room temperature
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 21 days
See individual tests
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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