Patients aged 21-24: If the Pap result is ASC-US then the HPV mRNA assay will be performed at an additional charge (CPT code(s): 87624). Chlamydia trachomatis (CT)/Neisseria gonorrhoeae (NG) RNA, TMA (CPT code(s): 87494), and Trichomonas vaginalis ("trich" or TV), Qualitative TMA, Pap Vial (CPT code(s): 87661) will also be performed.
Patients aged 25-29: If the Pap result is ASC-US then the HPV mRNA assay will be performed at an additional charge (CPT code(s): 87624). CT/NG RNA, TMA (CPT code(s): 87494), and TV, Qualitative TMA, Pap Vial (CPT code(s): 87661) will also be performed.
Patients aged 30-65: If the Pap result is negative and the HPV mRNA screen (CPT code(s): 87624) is positive (detected), then HPV mRNA Genotypes 16, 18/45 will be performed at an additional charge (CPT code(s): 87625). CT/NG RNA, TMA (CPT code(s): 87494), and TV, Qualitative TMA, Pap Vial (CPT code(s): 87661) will also be performed.
Pap results requiring physician interpretation will be performed at an additional charge (CPT Code(s): 88141; HCPCS: G0124).
Pap: Microscopy with Computer-imaging
HPV/CT/NG/Trich: Transcription Mediated Amplification (TMA)
The analytical performance characteristics of this assay, when used to test SurePath™ specimens have been determined by Quest Diagnostics.
Age-Based Pap Screening and CT/NG/Trich,Cervical Cancer Screening Age-Based w/ CT/NG/Trich,Age Based Smart Codes Pap Screening,Smart Codes for Age Based Pap Screen
Specimen requirements | |
|---|---|
| Patient preparation | None Specified |
| Preferred specimen(s) | Pap sample collected in 1 ThinPrep® pap vial or pap sample collected in 1 SurePath™ pap vial |
| Minimum volume | 1 ThinPrep pap vial • 1 SurePath pap vial |
| Collection instructions | For instructions refer to //www.questdiagnostics.com/dms/Documents/Other/Specimen_Collection_and_Transport_Guide_2019.pdf |
| Transport container | 1 ThinPrep pap vial or 1 SurePath pap vial |
| Transport temperature | Room temperature |
| Specimen stability | SurePath Pap - SurePath Pap Vial Room Temperature: 28 days Refrigerated: 6 months Frozen: Unacceptable SurePath HPV - SurePath Pap Vial Room temperature: 7 days Refrigerated: 7 days Frozen: Unacceptable SurePath HPV - SurePath Preservative Fluid in Aptima® Transfer Tube Room temperature: 7 days Refrigerated: 7 days Frozen: Unacceptable SurePath CT/NG - SurePath Pap Vial Room temperature: 4 days Refrigerated: Unacceptable Frozen: Unacceptable SurePath CT/NG - SurePath Preservative Fluid in Aptima® Transfer Tube Room temperature: 14 days Refrigerated: 14 days Frozen: Unacceptable ThinPrep Pap Room temperature: 42 days Refrigerated: Unacceptable Frozen: Unacceptable HPV - ThinPrep Pap Vial Room temperature: 30 days Refrigerated: 105 days Frozen: Unacceptable ThinPrep Pap Vial in Aptima® Transfer Tube Room temperature: 60 days Refrigerated: 60 days Frozen: 2 years CT/NG - ThinPrep Pap Vial Room temperature: 30 days Refrigerated: 30 days Frozen: Unacceptable CT/NG - ThinPrep Pap Vial in Aptima® Transfer Tube Room temperature: 14 days Refrigerated: 30 days Frozen: 1 year Trich ThinPrep Pap Vial Room temperature: 30 days Refrigerated: 30 days Frozen: Unacceptable Trich ThinPrep Pap in Aptima® Transfer Tube Room temperature: 14 days Refrigerated: 30 days Frozen: 1 year Refer to local service area for specimen retention. |
| Reject criteria | ThinPrep vials received refrigerated or frozen • Swabs • Cervical swabs in Digene® HC cervical sampler • Digene® vials • SurePath vials without the head of the collection device(s) in the fluid • SurePath vials received frozen |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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