Antiphospholipid Syndrome Evaluation Panel with Reflexes

Antiphospholipid Syndrome Evaluation Panel with Reflexes

Test Code

91248
86146 (x3), 86147 (x3), 83516 (x2), 85613
91248
86146 (x3), 86147 (x3), 83516 (x2), 85613
This test is not available in all locations. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Antiphospholipid Syndrome Evaluation Panel with Reflexes - The antiphospholipid antibody syndrome (APS) is a clinical-pathologic correlation that includes a clinical event (e.g. arterial or venous thrombosis, pregnancy morbidity) and persistent positive antiphospholipid antibodies (IgM, IgG Cardiolipin or b2GPI antibodies greater than the 99th percentile; or a lupus anticoagulant). International consensus guidelines for APS suggest waiting at least 12 weeks before retesting to confirm antibody persistence. The Systemic Lupus International Collaborating Clinics immunological classification criteria for systemic lupus erythematosus (SLE) include testing ...

Test Resources

None found for this test
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Test Details

Includes

  • Beta-2-Glycoprotein I Antibodies (IgG, IgA, IgM)
    Phosphatidylserine/Prothrombin (PS/PT) Antibodies (IgG, IgM)
    Cardiolipin Antibodies (IgA, IgG, IgM)
    dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix

    If dRVVT Screen is prolonged (>45 seconds), then dRVVT Confirm will be performed at an additional charge (CPT code(s): 85597).
    If dRVVT Confirm is positive, then dRVVT 1:1 Mixing Study will be performed at an additional charge (CPT code(s): 85613).

Methodology

Clot Detection • Immunoassay (IA)

Reference Range(s)

See individual tests

LOINC® Codes, Performing Laboratory

Service Area must be determined
Beta-2-Glycoprotein I Antibodies (IgG, IgA, IgM)
Phosphatidylserine/Prothrombin (PS/PT) Antibodies (IgG, IgM)
Cardiolipin Antibodies (IgA, IgG, IgM)
dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix

If dRVVT Screen is prolonged (>45 seconds), then dRVVT Confirm will be performed at an additional charge (CPT code(s): 85597).
If dRVVT Confirm is positive, then dRVVT 1:1 Mixing Study will be performed at an additional charge (CPT code(s): 85613).

Methodology

Clot Detection • Immunoassay (IA)

Reference Range(s)

See individual tests
Service Area must be determined

Preferred Specimen(s)

⁠⁠⁠⁠⁠⁠⁠1 mL frozen platelet-poor plasma collected in each of three 3.2% sodium citrate (light blue-top) tubes

Minimum Volume

0.5 mL each specimen

Transport Container

Transport tube(s)

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: Unacceptable
    Refrigerated: Unacceptable
    Frozen: 30 days

Reject Criteria

Hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined
⁠⁠⁠⁠⁠⁠⁠1 mL frozen platelet-poor plasma collected in each of three 3.2% sodium citrate (light blue-top) tubes
0.5 mL each specimen
Transport tube(s)
Frozen
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days
Hemolysis • Grossly lipemic
Service Area must be determined
This test is not available in all locations. Please provide ACCOUNT INFORMATION NEEDED to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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