Beta-2-Glycoprotein I Antibodies (IgG, IgM)

Test Code

91244

CPT Code(s)

86146 (x2)

Test Code

91244

CPT Code(s)

86146 (x2)

This test is not available in all locations. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Beta-2-Glycoprotein I Antibodies (IgG, IgM) - Beta-2-Glycoprotein 1 (also known as apolipoprotein H), is a cofactor in antiphospholipid antibody binding and is the critical antigen in the antiphospholipid antibody syndrome. The presence of high titer IgG/IgM beta-2-glycoprotein 1 antibodies is one criteria for the diagnosis of antiphospholipid antibody syndrome.

Test Resources

None found for this test
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Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

B2-Glycoprotein I (IgG) Ab	<20 U/mL Antibody not detected ≥20 U/mL Antibody detected
B2-Glycoprotein I (IgM) Ab	<20 U/mL Antibody not detected ≥20 U/mL Antibody detected

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Reference Range(s)

B2-Glycoprotein I (IgG) Ab	<20 U/mL Antibody not detected ≥20 U/mL Antibody detected
B2-Glycoprotein I (IgM) Ab	<20 U/mL Antibody not detected ≥20 U/mL Antibody detected

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

2 mL plasma collected in a 3.2% sodium citrate (light blue-top) tube

Alternative Specimen(s)

Serum

Minimum Volume

1 mL

Collection Instructions

Plasma: Centrifuge light blue-top tube 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL).

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

2 mL plasma collected in a 3.2% sodium citrate (light blue-top) tube

Alternative Specimen(s)

Serum

Minimum Volume

1 mL

Collection Instructions

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined

This test is not available in all locations. Please provide ACCOUNT INFORMATION NEEDED to confirm Test Code for the lab that services your account or to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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