Febrile Antibodies Panel
Test Code
91121
86757 (x4), 86622 (x2), 86768 (x5)
Clinical Significance
Febrile Antibodies Panel -
This panel comprises antibody testing for infections caused by Ricketssia rickettsii, Richetssia typhi, Salmonella, and Brucella in patients with fever. A 4-fold change in titers of antibodies between acute and convalescent sera confirms the infection. This panel provides targeted identification of antibodies, which supports differential diagnosis and can provide evidence of exposure.
R rickettsii causes Rocky Mountain spotted fever (RMSF), the most severe rickettsial disease in the United States. RMSF is transmitted via several species of ticks ...
Test Resources
Test Details
Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers
Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers
Salmonella, Total Antibody, EIA (Salmonella H Type a, Salmonella H Type b, Salmonella H Type d, Salmonella O Type Vi, Salmonella O Type D)
Brucella Antibodies (IgG, IgM), EIA with Reflex to Agglutination
If Rickettsia (RMSF) screen is Detected, IgG or IgM, then the appropriate Titer will be performed at an additional charge (CPT code(s) 86317 per titer performed).
If Rickettsia (Typhus Fever) screen is Detected, IgG or IgM, then the appropriate Titer will be performed at an additional charge (CPT code(s) 86317 per titer performed).
If Brucella IgM is ≥1.10, then Brucella Antibody Agglutination will be performed at an additional charge (CPT code(s): 86622).
Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers
Salmonella, Total Antibody, EIA (Salmonella H Type a, Salmonella H Type b, Salmonella H Type d, Salmonella O Type Vi, Salmonella O Type D)
Brucella Antibodies (IgG, IgM), EIA with Reflex to Agglutination
If Rickettsia (RMSF) screen is Detected, IgG or IgM, then the appropriate Titer will be performed at an additional charge (CPT code(s) 86317 per titer performed).
If Rickettsia (Typhus Fever) screen is Detected, IgG or IgM, then the appropriate Titer will be performed at an additional charge (CPT code(s) 86317 per titer performed).
If Brucella IgM is ≥1.10, then Brucella Antibody Agglutination will be performed at an additional charge (CPT code(s): 86622).
Methodology
See individual tests
Reference Range(s)
| RMSF IgG | Not detected |
| RMSF IgM | Not detected |
| R. typhi IgG | Not detected |
| R. typhi IgM | Not detected |
| Salmonella H, Type a | Negative |
| Salmonella H, Type b | Negative |
| Salmonella H, Type d | Negative |
| Salmonella O, Type Vi | Negative |
| Salmonella O, Type D | Negative |
| Brucella IgG | <0.80 |
| Brucella IgM | <0.80 |
Preferred Specimen(s)
3 mL serum
Minimum Volume
0.8 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 days
Setup Schedule
3 mL serum
0.8 mL
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days