Ashkenazi Jewish Panel (11 Tests)

Test Code

90891

CPT Code(s)

81412

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Test Code

90891

CPT Code(s)

81412

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Ashkenazi Jewish Panel (11 Tests) - This panel consists of the diseases frequent in the Ashkenazi Jewish population that have been recommended for population based carrier screening by the American College of Obstetricians and Gynecologists (ACOG) and/or American College of Medical Genetics and Genomics (ACMG), with two additional conditions. This panel screens for Cystic Fibrosis, Tay-Sachs (DNA), Canavan Disease, Familial Dysautonomia, Gaucher Disease, Fanconi Anemia Type C, Bloom Syndrome, Niemann-Pick Disease Type A, Mucolipidosis Type IV, Glycogen Storage Disease, and Maple Syrup Urine Disease (AJ Founder Mutations).

Test Resources

None found for this test
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Test Details

Includes

Cystic Fibrosis, Canavan Disease, Gaucher Disease, Fanconi Anemia, Bloom Syndrome, Tay-Sachs Mutation, Familial Dysautonomia, Niemann-Pick Disease, Mucolipidosis Type IV, Glycogen Storage Disease, MSUD Mutation (Jewish)

Methodology

Multiplex PCR • Massively Parallel Sequencing • Polymerase Chain Reaction (PCR) • Next Generation Sequencing

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See Laboratory report

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

Cystic Fibrosis, Canavan Disease, Gaucher Disease, Fanconi Anemia, Bloom Syndrome, Tay-Sachs Mutation, Familial Dysautonomia, Niemann-Pick Disease, Mucolipidosis Type IV, Glycogen Storage Disease, MSUD Mutation (Jewish)

Methodology

Multiplex PCR • Massively Parallel Sequencing • Polymerase Chain Reaction (PCR) • Next Generation Sequencing

Assay Category

Reference Range(s)

See Laboratory report

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

4 mL (x3) whole blood collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

Whole blood collected in: EDTA (royal-blue) top tube (x3), sodium heparin (green-top) tube (x3) or ACD solution A (yellow-top) tube (x3)

Minimum Volume

1.3 mL (x3)

Collection Instructions

Specimen stability is crucial. Store and ship at room temperature immediately. Do not freeze.

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable

Reject Criteria

Received frozen

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

4 mL (x3) whole blood collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

Whole blood collected in: EDTA (royal-blue) top tube (x3), sodium heparin (green-top) tube (x3) or ACD solution A (yellow-top) tube (x3)

Minimum Volume

1.3 mL (x3)

Collection Instructions

Specimen stability is crucial. Store and ship at room temperature immediately. Do not freeze.

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable

Reject Criteria

Received frozen

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.