Clorazepate (Tranxene®)

Test Code

90854

CPT Code(s)

80299

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Test Code

90854

CPT Code(s)

80299

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Clorazepate (Tranxene®) - Orally administered clorazepate is rapidly decarboxylated to its metabolite, nordiazepam. There is essentially no circulating patent drug. Nordiazepam elimination half-life is about 40 to 50 hours. Plasma levels of nordiazepam increase proportionally with clorazepate dose and show moderate accumulation with repeated administration.

Test Resources

None found for this test
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Test Details

Methodology

Chromatography/Mass Spectrometry

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Nordiazepam

100-500 ng/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Chromatography/Mass Spectrometry

Assay Category

Reference Range(s)

Nordiazepam

100-500 ng/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

2 mL serum collected in a red-top tube (no gel)

Alternative Specimen(s)

Plasma collected in: EDTA (lavender-top) tube or ACD (yellow-top) tube

Minimum Volume

1 mL

Collection Instructions

Note: Assayed as its primary metabolite, Nordiazepam.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 60 days

Reject Criteria

Serum Separator Tubes (SST) are not acceptable; use polypropylene tubes • Received room temperature

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

2 mL serum collected in a red-top tube (no gel)

Alternative Specimen(s)

Plasma collected in: EDTA (lavender-top) tube or ACD (yellow-top) tube

Minimum Volume

1 mL

Collection Instructions

Note: Assayed as its primary metabolite, Nordiazepam.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 60 days

Reject Criteria

Serum Separator Tubes (SST) are not acceptable; use polypropylene tubes • Received room temperature

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.