CEBPA Mutation Analysis, Extracted DNA

Test Code

90813

CPT Code(s)

81218

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Test Code

90813

CPT Code(s)

81218

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

CEBPA Mutation Analysis, Extracted DNA - Accurate testing for CEBPA mutations is important for identification of the prognostically significant AML subtype, especially CN-AML. AML with mutated CEBPA is a provisional disease entity in the 2008 World Health Organization classification of leukemias. CEBPA constitutes a key prognostic AML panel together with FLT-3 and NPM1.

Test Resources

None found for this test
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Test Details

Methodology

Next Generation Sequencing

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

CEBPA Mutation

Not detected

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Next Generation Sequencing

Assay Category

Reference Range(s)

CEBPA Mutation

Not detected

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

Extracted DNA

Minimum Volume

0.03 mL

Collection Instructions

DNA is to be shipped frozen. Do not thaw. Minimum and absolute minimum volume is 0.03 mL.
Ship DNA immediately after extraction is performed. DNA must remain frozen until testing.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: See Collection Instructions

Reject Criteria

Received room temperature • Received refrigerated

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

Extracted DNA

Minimum Volume

0.03 mL

Collection Instructions

DNA is to be shipped frozen. Do not thaw. Minimum and absolute minimum volume is 0.03 mL.
Ship DNA immediately after extraction is performed. DNA must remain frozen until testing.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: See Collection Instructions

Reject Criteria

Received room temperature • Received refrigerated

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.