Spectrophotometry (SP)
Specimen requirements | |
|---|---|
| Patient preparation | The assay manufacturer Beckman Coulter advises: N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol and uric acid where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours. |
| Preferred specimen(s) | 1 mL serum |
| Alternative specimen(s) | Sodium heparin (green-top) tube • Lithium heparin (green-top) tube |
| Minimum volume | 0.5 mL |
| Collection instructions | Note: N-acetyl-p-benzoquinone imine (NAPQI) (metabolite of acetaminophen) will generate erroneously low results in samples for patients that have taken toxic doses of acetaminophen. |
| Transport container | Serum separator tube (SST) |
| Transport temperature | Room temperature |
| Specimen stability | Serum and plasma Room temperature: 72 hours Refrigerated: 7 days Frozen: 28 days |
| Reject criteria | Anticoagulants other than heparin |
| Male (mg/dL) | Female (mg/dL) | ||||
| <1 Month | 1.5-3.9 | 1.5-4.6 | |||
| 1-11 Months | 1.5-5.6 | 1.5-5.4 | |||
| 1-3 Years | 2.1-5.6 | 1.8-5.0 | |||
| 4-6 Years | 1.8-5.5 | 2.0-5.1 | |||
| 7-9 Years | 1.8-5.4 | 1.8-5.5 | |||
| 10-12 Years | 2.2-5.8 | 2.5-5.9 | |||
| 13-15 Years | 3.1-7.0 | 2.2-6.4 | |||
| 16-18 Years | 2.1-7.6 | 2.4-6.6 | |||
| ≥19 Years | 4.0-8.0 | 2.5-7.0 |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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