Uric Acid

Uric Acid

Test Code

905
84550
905
84550
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano | Quest Nichols Institute -San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Uric Acid - Serum uric acid measurements are useful in the diagnosis and treatment of numerous renal and metabolic disorders, including renal failure, gout, leukemia, psoriasis, starvation or other wasting conditions, and in patients receiving cytotoxic drugs.

Test Resources

Clinical Focus

Autoimmune Rheumatic and Related Diseases

Test Details

Patient Preparation

The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for...cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Methodology

Spectrophotometry (SP)

Reference Range(s)

  Male
(mg/dL) 		Female
(mg/dL)
<1 Month

1.5-3.9

 1.5-4.6
1-11 Months 1.5-5.6 1.5-5.4
1-3 Years 2.1-5.6 1.8-5.0
4-6 Years 1.8-5.5 2.0-5.1
7-9 Years 1.8-5.4 1.8-5.5
10-12 Years 2.2-5.8 2.5-5.9
13-15 Years 3.1-7.0 2.2-6.4
16-18 Years 2.1-7.6 2.4-6.6
≥19 Years 4.0-8.0 2.5-7.0

LOINC® Codes, Performing Laboratory

Service Area must be determined
The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for...cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Methodology

Spectrophotometry (SP)

Reference Range(s)

  Male
(mg/dL) 		Female
(mg/dL)
<1 Month

1.5-3.9

 1.5-4.6
1-11 Months 1.5-5.6 1.5-5.4
1-3 Years 2.1-5.6 1.8-5.0
4-6 Years 1.8-5.5 2.0-5.1
7-9 Years 1.8-5.4 1.8-5.5
10-12 Years 2.2-5.8 2.5-5.9
13-15 Years 3.1-7.0 2.2-6.4
16-18 Years 2.1-7.6 2.4-6.6
≥19 Years 4.0-8.0 2.5-7.0
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Alternative Specimen(s)

Sodium heparin (green-top) tube • Lithium heparin (green-top) tube

Minimum Volume

0.5 mL

Collection Instructions

Note: N-acetyl-p-benzoquinone imine (NAPQI) (metabolite of acetaminophen) will generate erroneously low results in samples for patients that have taken toxic doses of acetaminophen.

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Specimen Stability

  • Serum and plasma
  • Room temperature: 72 hours
  • Refrigerated: 7 days
  • Frozen: 28 days

Reject Criteria

Anticoagulants other than heparin

Setup Schedule

Service Area must be determined
1 mL serum
Sodium heparin (green-top) tube • Lithium heparin (green-top) tube
0.5 mL
Note: N-acetyl-p-benzoquinone imine (NAPQI) (metabolite of acetaminophen) will generate erroneously low results in samples for patients that have taken toxic doses of acetaminophen.
Serum separator tube (SST)
Room temperature
Serum and plasma
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 28 days
Anticoagulants other than heparin
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano | Quest Nichols Institute -San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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