Cholinesterase, Serum, Plasma, RBC (CA Clients)
Test Code
Clinical Significance
Cholinesterase, Serum, Plasma, RBC (CA Clients) - True cholinesterase (RBC and plasma) activity is decreased in individuals with exposure to organophosphorous insecticides. True cholinesterase, found in erythrocytes and nerve tissue, is responsible for inactivating acetylcholinesterase at nerve endings. With decreased enzyme activity, patients may display a range of nervous system dysfunction. Analysis of RBC and serum or plasma activity is useful in monitoring exposure and recovery.
Test Resources
Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Test Details
Methodology
This test code is California patient testing. For non-California testing, use test code 39481.
Reference Range(s)
| Cholinesterase, Serum | |
| Male | 3342-7586 IU/L |
| Female | 2673-6592 IU/L |
| Cholinesterase, RBC | 9572-15031 IU/L |
| Cholinesterase, Plasma | |
| Male | 3334-7031 IU/L |
| Female | 2504-6297 IU/L |
Preferred Specimen(s)
5 mL uncentrifuged whole blood collected in an EDTA (lavender-top) tube and
1 mL plasma collected in an EDTA (lavender-top) tube and
1 mL serum
Alternative Specimen(s)
Plasma collected in: PPT potassium EDTA (white-top) tube
Minimum Volume
4 mL whole blood • 0.5 mL plasma • 0.5 mL serum
Collection Instructions
Transfer plasma and serum to transport tubes and send refrigerated with whole blood.
Note: PPT potassium EDTA (white-top) tubes should be centrifuged within 24 hours
Transport Container
EDTA (lavender-top) tube and transport tube(s)
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 24 hours
- Refrigerated: 7 days
- Frozen: Unacceptable
Reject Criteria
Hemolysis • Lipemia • Received room temperature • Received frozen
Setup Schedule
1 mL plasma collected in an EDTA (lavender-top) tube and
1 mL serum
Note: PPT potassium EDTA (white-top) tubes should be centrifuged within 24 hours
Refrigerated: 7 days
Frozen: Unacceptable