Cholinesterase, Serum, Plasma, RBC (CA Clients)

Cholinesterase, Serum, Plasma, RBC (CA Clients)

Test Code

90369
82480 (x2), 82482
90369
82480 (x2), 82482
This test is not available in all locations. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Cholinesterase, Serum, Plasma, RBC (CA Clients) - True cholinesterase (RBC and plasma) activity is decreased in individuals with exposure to organophosphorous insecticides. True cholinesterase, found in erythrocytes and nerve tissue, is responsible for inactivating acetylcholinesterase at nerve endings. With decreased enzyme activity, patients may display a range of nervous system dysfunction. Analysis of RBC and serum or plasma activity is useful in monitoring exposure and recovery.

Test Resources

None found for this test
Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.

Test Details

Methodology

Kinetic Spectrophotometric (KS)

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

This test code is California patient testing. For non-California testing, use test code 39481.

Reference Range(s)

Cholinesterase, Serum  
  Male 3342-7586 IU/L
  Female 2673-6592 IU/L
Cholinesterase, RBC 9572-15031 IU/L
Cholinesterase, Plasma  
  Male 3334-7031 IU/L
  Female 2504-6297 IU/L

LOINC® Codes, Performing Laboratory

Methodology

Kinetic Spectrophotometric (KS)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

This test code is California patient testing. For non-California testing, use test code 39481.

Reference Range(s)

Cholinesterase, Serum  
  Male 3342-7586 IU/L
  Female 2673-6592 IU/L
Cholinesterase, RBC 9572-15031 IU/L
Cholinesterase, Plasma  
  Male 3334-7031 IU/L
  Female 2504-6297 IU/L

Preferred Specimen(s)

5 mL uncentrifuged whole blood collected in an EDTA (lavender-top) tube and
1 mL plasma collected in an EDTA (lavender-top) tube and
1 mL serum

Alternative Specimen(s)

Plasma collected in: PPT potassium EDTA (white-top) tube

Minimum Volume

4 mL whole blood • 0.5 mL plasma • 0.5 mL serum

Collection Instructions

Transfer plasma and serum to transport tubes and send refrigerated with whole blood.

Note: PPT potassium EDTA (white-top) tubes should be centrifuged within 24 hours

Transport Container

EDTA (lavender-top) tube and transport tube(s)

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 24 hours
  • Refrigerated: 7 days
  • Frozen: Unacceptable

Reject Criteria

Hemolysis • Lipemia • Received room temperature • Received frozen

Setup Schedule

5 mL uncentrifuged whole blood collected in an EDTA (lavender-top) tube and
1 mL plasma collected in an EDTA (lavender-top) tube and
1 mL serum
Plasma collected in: PPT potassium EDTA (white-top) tube
4 mL whole blood • 0.5 mL plasma • 0.5 mL serum
Transfer plasma and serum to transport tubes and send refrigerated with whole blood.

Note: PPT potassium EDTA (white-top) tubes should be centrifuged within 24 hours
EDTA (lavender-top) tube and transport tube(s)
Refrigerated (cold packs)
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: Unacceptable
Hemolysis • Lipemia • Received room temperature • Received frozen
This test is not available in all locations. Please provide ACCOUNT INFORMATION NEEDED to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.