Sensory-Motor Neuropathy Antibody Panel (Ganglioside)

Test code

90129

CPT code(s)*

83520 (x9)

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical significance

Sensory-Motor Neuropathy Antibody Panel (Ganglioside) - The presence of antibodies to the gangliosides GM1, Asialo-GM1, GD1a and GD1b has been associated with motor and sensorimotor neuropathies. High titers of antibody to GM1 are most typical of multifocal motor neuropathy; however, antibodies to other gangliosides are often present. In most cases of chronic immune neuropathies, anti-ganglioside antibodies are IgM class. IgG antibodies have been reported less often, generally associated with acute conditions. Many reports have found increased anti-asialo-GM1 antibody titers in patients with multifocal motor neuropathy, lower motor neuron disease, sensorimotor neuropathy,…

Test resources

Clinical focus

New

Immune-Mediated Peripheral Neuropathies: Laboratory Support of Diagnosis

Details

Test details

The information below details the components of this test. For overall setup schedule, see Performing lab & setup schedule.

Included components

Test code	Test name	Orderable separately	Setup schedule
%39462	GANGLIOSIDE ASIALO GM 1ANTIBODY (IGG), EIA	No	Not provided
%38836	GANGLIOSIDE ASIALO GM 1ANTIBODY (IGM), EIA	No	Not provided
%38916	GANGLIOSIDE GD1A ANTIBODY(IGG), EIA	No	Not provided
%38964	GANGLIOSIDE GD1A ANTIBODY(IGM), EIA	No	Not provided
%39461	GANGLIOSIDE GD1B ANTIBODY(IGG), EIA	No	Not provided
%37439	GANGLIOSIDE GD1B ANTIBODY(IGM), EIA	No	Not provided
%37093	GANGLIOSIDE GM 1 ABS(IGG AND IGM ), EIA	No	Not provided
%34144	GANGLIOSIDE GQ1B AB(IGG), EIA	No	Not provided

Includes

Ganglioside GM-1 Antibodies (IgG, IgM), EIA
Ganglioside GD1a Antibody (IgG, IgM), EIA
Ganglioside GD1b Antibody (IgG, IgM), EIA
Ganglioside GQ1b Antibody (IgG), EIA
Ganglioside Asialo-GM-1 Antibody (IgG, IgM), EIA

Methodology

Immunoassay (IA)

Specimen requirements
Patient preparation	Overnight fasting is preferred
Preferred specimen(s)	3 mL serum
Minimum volume	1.6 mL
Transport container	Transport tube
Transport temperature	Refrigerated (cold packs)
Specimen stability	Room temperature: 24 hours Refrigerated: 7 days Frozen: 21 days
Reject criteria	Received room temperature

Reference range(s)

See Laboratory Report

LOINC® codes

The Result and LOINC® information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table are not orderable Test Codes

Result code	Result name	LOINC code	Component name
85991299	GANGLIOSIDE GM 1 ANTIBODY (IGG), EIA	43240-1	Ganglioside GM1 Ab.IgG
85991300	GM 1 AB (IGM)	43241-9	Ganglioside GM1 Ab.IgM
85992165	GANGLIOSIDE GD1B ANTIBODY (IGM), EIA	13661-4	Ganglioside GD1b Ab.IgM
85993209	GANGLIOSIDE GQ1B AB (IGG), EIA	14254-7	Ganglioside GQ1b Ab.IgG
85995733	GANGLIOSIDE ASIALO GM 1 ANTIBODY (IGM), EIA	10359-8	Asialoganglioside GM1 Ab.IgM
85996005	GANGLIOSIDE GD1A ANTIBODY (IGG), EIA	21283-7	Ganglioside GD1a Ab.IgG
85996006	GANGLIOSIDE GD1A ANTIBODY (IGM), EIA	21282-9	Ganglioside GD1a Ab.IgM
85996324	GANGLIOSIDE GD1B ANTIBODY (IGG), EIA	13662-2	Ganglioside GD1b Ab.IgG
85996325	GANGLIOSIDE ASIALO GM 1 ANTIBODY (IGG), EIA	13663-0	Asialoganglioside GM1 Ab.IgG

Performing lab & setup schedule

Performing laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Setup schedule

Information not provided in New England (MA, ME, RI, VT, Northern CT, NH) – Contact lab or Customer service to determine turnaround time

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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