Sensory-Motor Neuropathy Antibody Panel (Ganglioside)
Test Code
Clinical Significance
Sensory-Motor Neuropathy Antibody Panel (Ganglioside) - The presence of antibodies to the gangliosides GM1, Asialo-GM1, GD1a and GD1b has been associated with motor and sensorimotor neuropathies. High titers of antibody to GM1 are most typical of multifocal motor neuropathy; however, antibodies to other gangliosides are often present. In most cases of chronic immune neuropathies, anti-ganglioside antibodies are IgM class. IgG antibodies have been reported less often, generally associated with acute conditions. Many reports have found increased anti-asialo-GM1 antibody titers in patients with multifocal motor neuropathy, lower motor neuron disease, sensorimotor ...
Test Resources
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Test Details
Ganglioside GD1a Antibody (IgG, IgM), EIA
Ganglioside GD1b Antibody (IgG, IgM), EIA
Ganglioside GQ1b Antibody (IgG), EIA
Ganglioside Asialo-GM-1 Antibody (IgG, IgM), EIA
Methodology
Reference Range(s)
Preferred Specimen(s)
3 mL serum
Minimum Volume
1.6 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 24 hours
- Refrigerated: 7 days
- Frozen: 21 days
Reject Criteria
Received room temperature
Setup Schedule
Refrigerated: 7 days
Frozen: 21 days