Miller Fisher Syndrome, Cranial Neuropathy Antibody Panel (Ganglioside)

Miller Fisher Syndrome, Cranial Neuropathy Antibody Panel (Ganglioside)

Test Code

90128
83520 (x4)
90128
83520 (x4)
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Miller Fisher Syndrome, Cranial Neuropathy Antibody Panel (Ganglioside) - Ganglioside GM-1 IgG antibody is associated with acute inflammatory demyelinating polyneuropathy and acute motor axonal neuropathy. GD1a IgG antibody may also be associated with acute motor axonal neuropathy. GD1b IgG antibody may be associated with acute motor and sensory axonal neuropathy with cerebellar ataxia or ataxic presentations of Guillain-Barré Syndrome. GQ1b IgG antibody is associated with the Miller-Fisher Syndrome.

Test Resources

None found for this test
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Test Details

Includes

  • Ganglioside GM-1 Antibody (IgG), EIA
  • Ganglioside GD1a Antibody (IgG), EIA
  • Ganglioside GD1b Antibody (IgG), EIA
  • Ganglioside GQ1b Antibody (IgG), EIA

Patient Preparation

Overnight fasting is preferred

Methodology

Immunoassay (IA)

Reference Range(s)

GM-1 Ab (IgG)<1:800 Titer
  Normal<1:800
  Moderately elevated1:800-1:3200
  Highly elevated≥1:6400
GD1a Ab (IgG)<1:100 Titer
GD1b Ab (IgG)<1:100 Titer
GQ1b Ab (IgG)<1:100 Titer

LOINC® Codes, Performing Laboratory

Service Area must be determined
Ganglioside GM-1 Antibody (IgG), EIA
Ganglioside GD1a Antibody (IgG), EIA
Ganglioside GD1b Antibody (IgG), EIA
Ganglioside GQ1b Antibody (IgG), EIA
Overnight fasting is preferred

Methodology

Immunoassay (IA)

Reference Range(s)

GM-1 Ab (IgG)<1:800 Titer
  Normal<1:800
  Moderately elevated1:800-1:3200
  Highly elevated≥1:6400
GD1a Ab (IgG)<1:100 Titer
GD1b Ab (IgG)<1:100 Titer
GQ1b Ab (IgG)<1:100 Titer
Service Area must be determined

Preferred Specimen(s)

2 mL serum

Minimum Volume

0.8 mL

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 24 hours
  • Refrigerated: 7 days
  • Frozen: 21 days

Reject Criteria

Received room temperature

Setup Schedule

Service Area must be determined
2 mL serum
0.8 mL
Transport tube
Refrigerated (cold packs)
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 21 days
Received room temperature
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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