Chronic Urticaria Panel 2 (Comprehensive)

Chronic Urticaria Panel 2 (Comprehensive)

Test Code

90123
83520, 84443, 86343, 86376, 86800
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
90123
83520, 84443, 86343, 86376, 86800
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Chronic Urticaria Panel 2 (Comprehensive) - Patients with a chronic form of urticaria who are positive with the functional Histamine Release (Chronic Urticaria) test have an autoimmune basis for their disease. A positive result does not indicate which autoantibody (anti-IgE or anti-Fc epsilon RI alpha chain) is present. A positive anti-IgE antibody does not exclude the presence of anti-Fc epsilon RI alpha chain antibody. Autoimmune thyroid disease coexists in approximately 25% of autoimmune chronic urticaria patients.

Test Resources

None found for this test
Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.

Test Details

Includes

  • Histamine Release (Chronic Urticaria)
  • Thyroid Peroxidase Antibodies (TPO)
  • Thyroglobulin Antibodies
  • TSH
  • IgE Antibody (Anti-IgE IgG)

Patient Preparation

Patients taking calcineurin inhibitors should stop their medication for 72 hours prior to draw.

Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks after angiography. According to the assay manufacturer Siemens: samples containing fluorescein can produce falsely depressed values.

Methodology

See individual tests

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See individual tests

LOINC® Codes, Performing Laboratory

Service Area must be determined
Histamine Release (Chronic Urticaria)
Thyroid Peroxidase Antibodies (TPO)
Thyroglobulin Antibodies
TSH
IgE Antibody (Anti-IgE IgG)
Patients taking calcineurin inhibitors should stop their medication for 72 hours prior to draw.

Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks after angiography. According to the assay manufacturer Siemens: samples containing fluorescein can produce falsely depressed values.

Methodology

See individual tests
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See individual tests
Service Area must be determined

Preferred Specimen(s)

6 mL serum collected in a red-top (no gel)

Minimum Volume

3 mL

Collection Instructions

Serum should be separated from the cells as soon as possible after visible clot formation (usually 15-30 minutes after collection).

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 7 days
  • Frozen: 28 days

Reject Criteria

Gross hemolysis • Moderate hemolysis • Lipemia • Icteric specimen • Serum separator tube (SST) • Sample other than serum • Heavy visible particulate matter

Setup Schedule

Service Area must be determined
6 mL serum collected in a red-top (no gel)
3 mL
Serum should be separated from the cells as soon as possible after visible clot formation (usually 15-30 minutes after collection).
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Gross hemolysis • Moderate hemolysis • Lipemia • Icteric specimen • Serum separator tube (SST) • Sample other than serum • Heavy visible particulate matter
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.

Customize the test information for your Service Area