TSH

Test code

899

CPT code(s)*

84443

**CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical significance

TSH - For differential diagnosis of primary, secondary, and tertiary hypothyroidism. Also useful in screening for hyperthyroidism. This assay allows adjustment of exogenous thyroxine dosage in hypothyroid patients and in patients on suppressive thyroxine therapy for thyroid neoplasia.

Test resources

New

Polycystic Ovary Syndrome (PCOS)

Thyroid Dysfunction in Nonpregnant Adults

Test summary

Cardiometabolic Disease Assessment (CMDA) Panel

Details

Test details

Methodology

Immunoassay (IA)

Alternative name(s)

Thyrotropin,3rd Generation TSH,2nd Generation TSH,Highly Sensitive TSH,Thyroid Stimulating Hormone

Specimen requirements
Patient preparation	Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks. According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra assay."
Preferred specimen(s)	1 mL serum
Minimum volume	0.7 mL
Transport container	Serum separator tube (SST)
Transport temperature	Room temperature
Specimen stability	Room temperature: 7 days Refrigerated: 7 days Frozen: 28 days
Reject criteria	Plasma

Reference range(s)

Reference Range(s)

Premature Infants, (28-36 weeks)
1st week of life	0.20-27.90 mIU/L

Term Infants, (>37 weeks)
serum or cord blood	1.00-39.00 mIU/L

1-2 days	3.20-34.60 mIU/L
3-4 days	0.70-15.40 mIU/L
5 days-4 weeks	1.70-9.10 mIU/L
1-11 months	0.80-8.20 mIU/L
1-19 years	0.50-4.30 mIU/L
≥20 years	0.40-4.50 mIU/L

Pregnancy
First Trimester	0.26-2.66 mIU/L
Second Trimester	0.55-2.73 mIU/L
Third Trimester	0.43-2.91 mIU/L

⁠⁠⁠⁠⁠⁠⁠
TSH levels decline rapidly during the first week of life in most children, but may remain transiently elevated in a few individuals despite normal free T4 levels. For proper interpretation of an abnormal TSH from a newborn thyroid screen, a Free T4 by Dialysis (test code 35167) or Total T4 (test code 867) should be considered.

LOINC® codes

The Result and LOINC® information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table are not orderable Test Codes

Result code	Result name	LOINC code	Component name
55080400	TSH	3016-3	Thyrotropin

Performing lab & setup schedule

Performing laboratory

Quest Diagnostics - East Region

Setup schedule

Set up: Mon-Sat (All shifts); Report available: 1 day

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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