Myeloperoxidase Antibody (MPO)

Myeloperoxidase Antibody (MPO)

Test Code

8796
86021
8796
86021
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Myeloperoxidase Antibody (MPO) - Autoimmune vasculitis diseases are characterized by abnormal immune responses that result in inflammation and necrosis of blood vessels. The immune dysfunction may be triggered by infection, autoimmune disease, or exposure to a drug; often the cause is unknown. ANCA-associated vasculitis diseases are often characterized by the size of the blood vessels involved. The diseases present with diverse clinical features and are often rapidly progressive, causing irreversible injury to the vessels of the organs affected, such as the kidneys and lungs.

Test Resources

Clinical Focus

Autoimmune Rheumatic and Related Diseases

Clinical Focus

Inflammatory Bowel Disease: Laboratory Support for Diagnosis and Management

Topic Brief

Laboratory Diagnosis of Peripheral Neuropathy

Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

<1.0 AI No antibody detected 
≥1.0 AI Antibody detected 

Alternative Name(s)

Anti-Myeloperoxidase,Churg-Strauss Syndrome,Crescentic Glomeruloephritis,MPO

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Reference Range(s)

<1.0 AI No antibody detected 
≥1.0 AI Antibody detected 

Alternative Name(s)

Anti-Myeloperoxidase,Churg-Strauss Syndrome,Crescentic Glomeruloephritis,MPO
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.3 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 30 days 

Reject Criteria

Gross hemolysis

Setup Schedule

Service Area must be determined
1 mL serum
0.3 mL
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days 
Gross hemolysis
Service Area must be determined
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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