TBG (Thyroxine Binding Globulin)

TBG (Thyroxine Binding Globulin)

Test Code

870
84442
870
84442
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

TBG (Thyroxine Binding Globulin) - Thyroxine-binding globulin (TBG), a glycoprotein produced in the liver, binds both thyroxine (T4) and triiodothyronine (T3) with high affinity. Because TBG accounts for 76% of plasma protein thyroxine-binding activity, an increase or decrease in its circulating level alters total concentrations of T4 and T3 in blood, leading to potential confusion with true thyroid gland dysfunction. A number of diseases and medications, as well as inherited alterations in TBG gene expression, can change the serum TBG concentration. Measurement of TBG is useful in distinguishing quantitative TBG derangements ...

Test Resources

Clinical Focus

Thyroid Dysfunction in Nonpregnant Adults

Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

Adult Male 12.7-25.1 mcg/mL
Adult Female 13.5-30.9 mcg/mL
Pediatric    
  4-6 Years 14.8-32.9 mcg/mL
  7-8 Years 16.3-30.7 mcg/mL
  9-10 Years 15.8-27.4 mcg/mL
  11 Years 15.5-27.4 mcg/mL
  12 Years 14.8-26.2 mcg/mL
  13 Years 13.8-25.2 mcg/mL
  14 Years 12.2-25.2 mcg/mL
  15 Years 10.8-23.8 mcg/mL
  16 Years 10.0-23.8 mcg/mL
  17 Years 8.5-23.1 mcg/mL

Alternative Name(s)

Thyroxine Binding Globulin

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Reference Range(s)

Adult Male 12.7-25.1 mcg/mL
Adult Female 13.5-30.9 mcg/mL
Pediatric    
  4-6 Years 14.8-32.9 mcg/mL
  7-8 Years 16.3-30.7 mcg/mL
  9-10 Years 15.8-27.4 mcg/mL
  11 Years 15.5-27.4 mcg/mL
  12 Years 14.8-26.2 mcg/mL
  13 Years 13.8-25.2 mcg/mL
  14 Years 12.2-25.2 mcg/mL
  15 Years 10.8-23.8 mcg/mL
  16 Years 10.0-23.8 mcg/mL
  17 Years 8.5-23.1 mcg/mL

Alternative Name(s)

Thyroxine Binding Globulin
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 7 days
  • Frozen: 28 days

Reject Criteria

Gross hemolysis

Setup Schedule

Service Area must be determined
1 mL serum
0.5 mL
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Gross hemolysis
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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