Sodium, 24-Hour Urine with Creatinine
Test Code
Clinical Significance
Sodium, 24-Hour Urine with Creatinine - The excretion of sodium varies with dietary intake. There is a diurnal variation of sodium excretion with excretion being greater during daytime than during the night. Decreased levels are seen in congestive heart failure, excessive sweating, diarrhea, pyloric obstruction, malabsorption and primary aldosteronism. Increased levels may be due to increased salt intake, failure of the adrenal glands, diabetic acidosis, salt losing renal disease, diuretic therapy and water deprivation dehydration. The creatinine value provides evidence of proper 24-hour urine collection.
Test Resources
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Test Details
Methodology
Reference Range(s)
Preferred Specimen(s)
10 mL aliquot of a 24-hour urine collected in a no preservative plastic urine container
Alternative Specimen(s)
Urine preserved with boric acid • Urine preserved with acetic acid • Urine preserved with HCl • Urinalysis transport tube (yellow-top, blue fill line, preservative tube)
Minimum Volume
2 mL
Collection Instructions
Record total volume and collection duration on specimen container and test requisition
Transport Container
Plastic urine container
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 7 days
- Frozen: 28 days
Setup Schedule
Refrigerated: 7 days
Frozen: 28 days