Direct LDL | Test Detail | Quest Diagnostics

Direct LDL

Test Code

8293

CPT Code(s)

83721

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Test Code

8293

CPT Code(s)

83721

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Direct LDL - LDL cholesterol is a key factor in the pathogenesis of atherosclerosis and Coronary Artery Disease (CAD), while HDL cholesterol has often been observed to have a protective effect. Even within the normal range of total cholesterol concentrations, an increase in LDL cholesterol can produce an associated increased risk for CAD. LDL cholesterol binds to receptor sites on macrophages in blood vessel walls inciting several changes to the blood wall which enhance atherosclerotic plaque development.

Test Resources

Clinical Focus

Polycystic Ovary Syndrome (PCOS)

Test Summary

LDL Cholesterol

Test Details

Patient Preparation

If a Direct LDL-cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection. If the Direct LDL cholesterol is ordered along with a lipid panel, then a fasting sample is not required.

Methodology

Enzymatic

Reference Range(s)

<20 Years	<110 mg/dL
≥20 Years	<100 mg/dL

Alternative Name(s)

DLDL,LDL Cholesterol, Direct,Low Density Lipoprotein,LDL Direct,Cholesterol, LDL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Patient Preparation

Methodology

Enzymatic

Reference Range(s)

<20 Years	<110 mg/dL
≥20 Years	<100 mg/dL

Alternative Name(s)

DLDL,LDL Cholesterol, Direct,Low Density Lipoprotein,LDL Direct,Cholesterol, LDL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Alternative Specimen(s)

Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube

Minimum Volume

0.5 mL

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 6 days
Refrigerated: 7 days
Frozen: 31 days

Reject Criteria

Anticoagulants other than heparin

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Alternative Specimen(s)

Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube

Minimum Volume

0.5 mL

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 6 days
Refrigerated: 7 days
Frozen: 31 days

Reject Criteria

Anticoagulants other than heparin

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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