Protein Electrophoresis, 24-Hour Urine (UPEP)
Test Code
Clinical Significance
Protein Electrophoresis, 24-Hour Urine (UPEP) - This test is used to analyze the protein content in urine. The proteins are separated into 5 major components: albumin, alpha-1, alpha-2, beta, and gamma. Interpretation of elevations, decreases, or visual changes in different components and/or associated patterns can provide information on various disease states, including inflammatory diseases, autoimmune diseases, different types of kidney injury, plasma cell disorders, and cancers [1,2].
UPEP is used to evaluate an individual with symptoms associated with potential monoclonal gammopathy, or when an individual has abnormally high total ...
Test Resources
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Test Details
CPT code 81050 may be added at an additional charge for volume measurement
Methodology
Reference Range(s)
Alternative Name(s)
Preferred Specimen(s)
25 mL 24-hour urine collected in an unpreserved, plastic urine container
Minimum Volume
15 mL
Collection Instructions
Record total volume on test requisition and specimen container
Transport Container
Plastic urine container
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 4 days
- Refrigerated: 5 days
- Frozen: 30 days
Reject Criteria
Acidified urine
Setup Schedule
Refrigerated: 5 days
Frozen: 30 days