Prolactin
Test Code
Clinical Significance
Prolactin -
During pregnancy and postpartum lactation, serum prolactin can increase 10- to 20-fold. Exercise, stress, and sleep also cause transient increases in prolactin levels. Consistently elevated serum prolactin levels (>30 ng/mL), in the absence of pregnancy and postpartum lactation, are indicative of hyperprolactinemia. Hypersecretion of prolactin can be caused by pituitary adenomas, hypothalamic disease, breast or chest wall stimulation, renal failure or hypothyroidism. A number of drugs, including many antidepressants, are also common causes of abnormally elevated prolactin levels. ...
Test Details
Overnight fasting is preferred
Methodology
Reference Range(s)
| Adult Males | 2.0-18.0 ng/mL | ||||
| Adult Females | |||||
| Non-Pregnant | 3.0-30.0 ng/mL | ||||
| Pregnant | 10.0-209.0 ng/mL | ||||
| Postmenopausal | 2.0-20.0 ng/mL |
Stages of Puberty (Tanner Stages)
| Female Observed | Male Observed | |
| Stage I | 3.6.12.0 ng/mL | ≤10.0 ng/mL |
| Stage II-III | 2.6-18.0 ng/mL | ≤6.1 ng/mL |
| Stage IV-V | 3.2-20.0 ng/mL | 2.8-11.0 ng/mL |
Preferred Specimen(s)
1 mL serum
Minimum Volume
0.5 mL
Transport Container
Serum separator tube (SST)
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 5 days
- Refrigerated: 7 days
- Frozen: 28 days
Setup Schedule
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 28 days