Cardiolipin Antibodies (IgA, IgG, IgM)

Test Code

7352

CPT Code(s)

86147 (x3)

Test Code

7352

CPT Code(s)

86147 (x3)

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Cardiolipin Antibodies (IgA, IgG, IgM) - Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly systemic lupus erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, and primary Sjögren's syndrome.

Test Resources

Test FAQ

Antiphospholipid Antibodies

Clinical Focus

Autoimmune Rheumatic and Related Diseases

Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

Cardiolipin Antibody (IgA)

Value	Interpretation
<20.0 APL-U/mL	Antibody not detected
≥20.0 APL-U/mL	Antibody detected

Cardiolipin Antibody (IgG)

Value	Interpretation
<20.0 GPL-U/mL	Antibody not detected
≥20.0 GPL-U/mL	Antibody detected

Cardiolipin Antibody (IgM)

Value	Interpretation
<20.0 MPL-U/mL	Antibody not detected
≥20.0 MPL-U/mL	Antibody detected

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Reference Range(s)

Cardiolipin Antibody (IgA)

Value	Interpretation
<20.0 APL-U/mL	Antibody not detected
≥20.0 APL-U/mL	Antibody detected

Cardiolipin Antibody (IgG)

Value	Interpretation
<20.0 GPL-U/mL	Antibody not detected
≥20.0 GPL-U/mL	Antibody detected

Cardiolipin Antibody (IgM)

Value	Interpretation
<20.0 MPL-U/mL	Antibody not detected
≥20.0 MPL-U/mL	Antibody detected

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL citrated plasma collected in a 3.2% sodium citrate (light blue-top) tube

Alternative Specimen(s)

Serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 mL citrated plasma collected in a 3.2% sodium citrate (light blue-top) tube

Alternative Specimen(s)

Serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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