Lupus Anticoagulant Evaluation with Reflex
Test code
CPT code(s)*
Clinical significance
Test resources
Specimen handling - specimen collection video
Details
Includes
PTT-LA and dRVVT with Reflex Confirmations
If PTT-LA Screen is prolonged (>40 seconds), then Hexagonal Phase Confirmation will be performed at an additional charge (CPT code(s): 85598).
If Hexagonal Phase Confirmation is positive or weakly positive, then Thrombin Clotting Time will be performed at an additional charge (CPT code(s): 85670).
If dRVVT Screen is prolonged (>45 seconds), then dRVVT Confirm will be performed at an additional charge (CPT code(s): 85597).
If dRVVT Confirm is positive, then dRVVT 1:1 Mixing Study will be performed at an additional charge (CPT code(s): 85613).
Methodology
Clot detection
Specimen requirements | |
|---|---|
| Patient preparation | None Specified |
| Preferred specimen(s) | 3 mL frozen, platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube |
| Minimum volume | 2 mL |
| Collection instructions | Platelet-poor plasma: Centrifuge light blue-top tube for 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice. |
| Transport container | Transport tube |
| Transport temperature | Frozen |
| Specimen stability | Room temperature: Unacceptable Refrigerated: Unacceptable Frozen: 30 days |
| Reject criteria | Hemolysis • Received thawed |
Reference Range(s)
| Lupus Anticoagulant | Not detected |
| PTT-LA Screen | ≤40 sec |
| dRVVT Screen | ≤45 sec |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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