Rickettsia Species DNA, Real-Time PCR

Rickettsia Species DNA, Real-Time PCR

Test Code

70191
87798
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
70191
87798
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Rickettsia Species DNA, Real-Time PCR - This assay allows for the detection of Rickettsia species DNA in whole blood from symptomatic patients, facilitating the diagnosis during the acute phase of the disease especially in severe cases. It can be used to aid in the diagnosis of Rocky Mountain spotted fever, epidemic and murine typhus and other tick bite fevers. This testing methodology may in some cases provide earlier diagnostic information when compared to serological methods. The collection of specimens should be done before implementation of antibiotic therapy; this test does not detect past or resolved infections. A not detected ...

Test Resources

Algorithm

An Approach to the Differential Diagnosis of Tick-borne Diseases

Algorithm

Serological Test Selection for the Differential Diagnosis of Tick-borne Diseases Based on Geographic Origin and Symptoms of Infection

Topic Brief

Tick-borne Disease: Laboratory Support of Diagnosis and Management

Test Details

Methodology

Real-Time Polymerase Chain Reaction

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Not detected

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Real-Time Polymerase Chain Reaction
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Not detected
Service Area must be determined

Preferred Specimen(s)

0.7 mL whole blood collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

1 tick collected in 70% alcohol

Minimum Volume

0.3 mL

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • ⁠⁠⁠⁠⁠⁠⁠Whole blood
    Room temperature: 48 hours
    Refrigerated: 14 days
    Frozen: 30 days

    Tick
    Room temperature: 7 days
    Refrigerated: 14 days
    Frozen: 30 days

Setup Schedule

Service Area must be determined
0.7 mL whole blood collected in an EDTA (lavender-top) tube
1 tick collected in 70% alcohol
0.3 mL
EDTA (lavender-top) tube
Refrigerated (cold packs)
⁠⁠⁠⁠⁠⁠⁠Whole blood
Room temperature: 48 hours
Refrigerated: 14 days
Frozen: 30 days

Tick
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Service Area must be determined
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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