ANCA Screen with Reflex to ANCA Titer
Test Code
70171
86036
Clinical Significance
ANCA Screen with Reflex to ANCA Titer - Testing for anti-neutrophil cytoplasmic antibodies (P-ANCA and or C-ANCA) has been found to be useful in establishing the diagnosis of suspected vascular diseases (e.g., crescentic glomerulonephritis, microscopic polyarteritis and churg-strauss syndrome), bowel disease (Crohn's Disease, ulcerative colitis, primary sclerosing cholangitis, and autoimmune hepatitis) as well as with other autoimmune diseases (drug-induced lupus, SLE, Felty's Syndrome).
ANCA has classically been divided into C-ANCA and P-ANCA depending on the immunofluorescent pattern observed. More recently the specific antigens ...
Test Resources
Test Details
If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86037 for each titer performed).
Methodology
Immunoassay (IA)
Reference Range(s)
| ANCA Screen | Negative |
| C-ANCA Titer | <1:20 |
| P-ANCA Titer | <1:20 |
| Atypical P-ANCA Titer | <1:20 |
Preferred Specimen(s)
1 mL serum
Minimum Volume
0.5 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 days
Reject Criteria
Gross hemolysis • Grossly lipemic
Setup Schedule
1 mL serum
0.5 mL
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Gross hemolysis • Grossly lipemic