Cytomegalovirus Antibodies (IgG, IgM)

Test Code

6732

CPT Code(s)

86644, 86645

Test Code

6732

CPT Code(s)

86644, 86645

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Cytomegalovirus Antibodies (IgG, IgM) - Intrauterine or congenital CMV infections occur in 0.5 to 2.2% of all live births. Symptomatic congenital infections usually occur in infants born to non-immune mothers who have primary infections during pregnancy. Latency and reactivation of CMV influence the interpretation of serological results. A single positive CMV IgG result is and indication of present or past infection. The presence of CMV IgM suggests a recent CMV exposure but does not differentiate between primary infection and reactivation.

Test Resources

Clinical Focus

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Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

Cytomegalovirus Antibody (IgG)

U/mL	Interpretation
<0.60	Negative
0.60-0.69	Equivocal
≥0.70	Positive

A positive result indicates that the patient has antibody to CMV. It does not differentiate between an active or past infection.

Cytomegalovirus Antibody (IgM)

AU/mL	Interpretation
<30.00	No antibody detected
30.00-34.99	Equivocal
≥35.00	Antibody detected

Results from any one IgM assay should not be used as a sole determinant of a current or recent infection. Because an IgM test can yield false positive results and low level IgM antibody may persist for more than 12 months post infection, reliance on a single test result could be misleading. Acute infection is best diagnosed by demonstrating the conversion of IgG from negative to positive. If an acute infection is suspected, consider obtaining a new specimen and submit for both IgG and IgM testing in two or more weeks.

Alternative Name(s)

CMV IgG, IgM Abs,CMV Antibody IgG, IgM

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Reference Range(s)

Cytomegalovirus Antibody (IgG)

U/mL	Interpretation
<0.60	Negative
0.60-0.69	Equivocal
≥0.70	Positive

A positive result indicates that the patient has antibody to CMV. It does not differentiate between an active or past infection.

Cytomegalovirus Antibody (IgM)

AU/mL	Interpretation
<30.00	No antibody detected
30.00-34.99	Equivocal
≥35.00	Antibody detected

Alternative Name(s)

CMV IgG, IgM Abs,CMV Antibody IgG, IgM

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1.5 mL serum

Minimum Volume

0.7 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1.5 mL serum

Minimum Volume

0.7 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric

Setup Schedule

Service Area must be determined

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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