Gastrin, 8 Specimens

Gastrin, 8 Specimens

Test Code

6720
82941, 82938 (x7)
6720
82941, 82938 (x7)
This test is not available in all locations. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Gastrin, 8 Specimens - For the diagnosis and monitoring of gastrin-secreting tumors, gastric ulcer, Zollinger-Ellison syndrome.

Test Resources

None found for this test
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Test Details

Patient Preparation

Overnight fasting (12 hours).
The serum secretin test requires patients to be off of antacids and anticholinergic medications for 12 hours prior to the test. Proton pump inhibitors should not be discontinued because of concern of complications (acute bleeding and/or perforation if acid suppression is discontinued).

Methodology

Immunoassay (IA)

Reference Range(s)

⁠⁠⁠⁠⁠⁠⁠Reference range applies to fasting specimen only

<5 YearsNot established
5-17 Years<65 pg/mL
≥18 Years≤100 pg/mL

Post secretion stimulation response
>200 pg/mL above basal levelPositive test

LOINC® Codes, Performing Laboratory

Service Area must be determined
Overnight fasting (12 hours).
The serum secretin test requires patients to be off of antacids and anticholinergic medications for 12 hours prior to the test. Proton pump inhibitors should not be discontinued because of concern of complications (acute bleeding and/or perforation if acid suppression is discontinued).

Methodology

Immunoassay (IA)

Reference Range(s)

⁠⁠⁠⁠⁠⁠⁠Reference range applies to fasting specimen only
<5 YearsNot established
5-17 Years<65 pg/mL
≥18 Years≤100 pg/mL

Post secretion stimulation response
>200 pg/mL above basal levelPositive test
Service Area must be determined

Preferred Specimen(s)

1 ml frozen serum per specimen

Minimum Volume

0.5 mL each specimen

Collection Instructions

Secretin Stimulation: The secretin used is a preparation from RepliGen (GIH Stimulation). For this protocol, 0.4 mcg of secretin per kilogram of body weight is infused by intravenous bolus. Serum for gastrin is collected at -10 minutes and -1 minute before secretin injection, and +2 minutes, +5, +10, +15, +20, and +30 minutes after secretin stimulation. Label each tube with time of collection.

Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Transport Container

Transport tube(s)

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: Unacceptable
  • Refrigerated: Unacceptable
  • Frozen: 28 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric • Received thawed

Setup Schedule

Service Area must be determined
1 ml frozen serum per specimen
0.5 mL each specimen
Secretin Stimulation: The secretin used is a preparation from RepliGen (GIH Stimulation). For this protocol, 0.4 mcg of secretin per kilogram of body weight is infused by intravenous bolus. Serum for gastrin is collected at -10 minutes and -1 minute before secretin injection, and +2 minutes, +5, +10, +15, +20, and +30 minutes after secretin stimulation. Label each tube with time of collection.

Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Transport tube(s)
Frozen
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 28 days
Gross hemolysis • Grossly lipemic • Grossly icteric • Received thawed
Service Area must be determined
This test is not available in all locations. Please provide ACCOUNT INFORMATION NEEDED to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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