Insulin Response to Glucose, 3 Specimens
Test Code
6695
83525 (x3)
Clinical Significance
Insulin Response to Glucose, 3 Specimens - The insulin response to glucose infusion is useful in evaluating patients with hypoglycemia and suspected insulin-resistance.
Test Resources
None found for this test
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Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Test Details
Overnight fasting is required.
High carbohydrate diet for 3 days before test. Patient NPO after midnight; glucose solution 1.75 g/kg body weight (maximum dose 75 g) orally administered after collection of fasting specimen.
High carbohydrate diet for 3 days before test. Patient NPO after midnight; glucose solution 1.75 g/kg body weight (maximum dose 75 g) orally administered after collection of fasting specimen.
Methodology
Immunoassay (IA)
Reference Range(s)
| Fasting | 2.0-18.4 uIU/mL |
| 30 Minutes Post Glucose | 6.0-86.0 uIU/mL |
| 60 Minutes Post Glucose | 8.0-112.0 uIU/mL |
| 90 Minutes Post Glucose | 5.0-68.0 uIU/mL |
| 120 Minutes Post Glucose | 5.0-55.0 uIU/mL |
| 150 Minutes Post Glucose | 3.0-46.0 uIU/mL |
| 180 Minutes Post Glucose | 3.0-20.0 uIU/mL |
| 240 Minutes Post Glucose | <15.0 uIU/mL |
| 300 Minutes Post Glucose | <8.0 uIU/mL |
These values are provided for general guidance only.
Preferred Specimen(s)
1 mL serum per specimen
Minimum Volume
0.5 mL per specimen
Collection Instructions
Draw fasting specimen. Collect 1 mL serum for each timed specimen post glucose dose. All tubes must be clearly marked with time drawn. Submit all tubes with one test requisition.
Reference ranges available: Fasting and 30, 60, 90, 120, 150, 180, 240 and 300 minutes post glucose.
Unable to add INSULIN testing unless sample was submitted frozen.
Transport Container
Transport tube(s)
Transport Temperature
Refrigerated (cold Packs)
Specimen Stability
- Room temperature: 8 hours
- Refrigerated: 7 days
- Frozen: 28 days
Reject Criteria
Hemolysis • Plasma • Grossly icteric
Setup Schedule
1 mL serum per specimen
0.5 mL per specimen
Draw fasting specimen. Collect 1 mL serum for each timed specimen post glucose dose. All tubes must be clearly marked with time drawn. Submit all tubes with one test requisition.
Reference ranges available: Fasting and 30, 60, 90, 120, 150, 180, 240 and 300 minutes post glucose.
Unable to add INSULIN testing unless sample was submitted frozen.
Reference ranges available: Fasting and 30, 60, 90, 120, 150, 180, 240 and 300 minutes post glucose.
Unable to add INSULIN testing unless sample was submitted frozen.
Transport tube(s)
Refrigerated (cold Packs)
Room temperature: 8 hours
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Hemolysis • Plasma • Grossly icteric