Myelin Basic Protein
Test Code
663
83873
In-home collection is not available in your area through Quest Mobile.
Clinical Significance
Myelin Basic Protein - The concentration of MBP is often increased in patients with demyelinating diseases such as multiple sclerosis and may be increased in patients with head injury, CNS trauma, tumor, stroke, and viral encephalitis.
Test Resources
None found for this test
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Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Test Details
Methodology
Radioimmunoassay (RIA)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
| ≤4.0 mcg/L | Negative |
| 4.1-6.0 mcg/L | Weakly positive |
| >6.0 mcg/L | Positive |
Alternative Name(s)
MBP
Preferred Specimen(s)
1.2 mL CSF
Minimum Volume
0.5 mL
Collection Instructions
CSF must be clear.
Do not centrifuge.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 21 days
Reject Criteria
Hemolysis • Xanthochromia/RBCs in CSF
Setup Schedule
1.2 mL CSF
0.5 mL
CSF must be clear.
Do not centrifuge.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Do not centrifuge.
CSF collection tube #4 is preferred. Submitting 4th lumbar puncture collection tube minimizes blood contamination.
Transport tube
Frozen
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Hemolysis • Xanthochromia/RBCs in CSF