Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers

Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers

Test Code

6419
86757 (x2)
6419
86757 (x2)
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers - Antigen specific IgG and IgM titers allow rapid diagnosis of infection by any of the spotted fever group of rickettsial agents. This group of agents include R. rickettsii (Rocky Mountain Spotted Fever) and R. akari (rickettsial pox), both seen in the continental United States.

Test Resources

Algorithm

An Approach to the Differential Diagnosis of Tick-borne Diseases

Algorithm

Serological Test Selection for the Differential Diagnosis of Tick-borne Diseases Based on Geographic Origin and Symptoms of Infection

Topic Brief

Tick-borne Disease: Laboratory Support of Diagnosis and Management

Test Details

Includes

  • If RMSF IgG is Detected, then RMSF IgG Titer will be performed at an additional charge (CPT code(s): 86317).
    If RMSF IgM is Detected, then RMSF IgM Titer will be performed at an additional charge (CPT code(s): 86317).

Methodology

Immunofluorescence Assay (IFA)

Reference Range(s)

  Screen Titer
RMSF (IgG) Not detected <1:64
RMSF (IgM) Not detected <1:64

Alternative Name(s)

Rocky Mountain Spotted Fever,Spotted Fever Typhus

LOINC® Codes, Performing Laboratory

Service Area must be determined
If RMSF IgG is Detected, then RMSF IgG Titer will be performed at an additional charge (CPT code(s): 86317).
If RMSF IgM is Detected, then RMSF IgM Titer will be performed at an additional charge (CPT code(s): 86317).

Methodology

Immunofluorescence Assay (IFA)

Reference Range(s)

  Screen Titer
RMSF (IgG) Not detected <1:64
RMSF (IgM) Not detected <1:64

Alternative Name(s)

Rocky Mountain Spotted Fever,Spotted Fever Typhus
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.2 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined
1 mL serum
0.2 mL
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Gross hemolysis • Grossly lipemic
Service Area must be determined
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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