CBC (includes Differential and Platelets)

Test code

6399

CPT code(s)*

85025

**CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical significance

CBC (includes Differential and Platelets) - A complete blood count is used as a screening test for various disease states to include: anemia, leukemia and inflammatory processes.

Test resources

Algorithm

Differential Diagnosis of Inflammatory Bowel Disease

Clinical focus

Inflammatory Bowel Disease: Laboratory Support for Diagnosis and Management

Viral Hepatitis: Laboratory Support for Diagnosis and Management

Test guide

New

Chronic Myeloid Leukemia: Laboratory Evaluation

Details

Test details

Includes

WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (Absolute and Percent - Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils)
⁠⁠⁠⁠⁠⁠⁠
If abnormal cells are noted on a manual review of the peripheral blood smear or if the automated differential information meets specific criteria, a full manual differential will be performed.

Methodology

Electronic Cell Sizing/Counting/Cytometry/Microscopy

Alternative name(s)

Coulter CBC,Complete Blood Count,CBC w/ Diff,CBC, Plt, RDW & Diff,CBC/Diff,CBC/Plt

Specimen requirements
Patient preparation	None Specified
Preferred specimen(s)	Whole blood from a full EDTA (lavender-top) tube
Alternative specimen(s)	Whole blood from a full EDTA (tan-top) tube
Minimum volume	Microtainer 0.5 mL • 1 mL whole blood EDTA tube
Collection instructions	Maintain specimen at room temperature. Do not refrigerate. If multiple draw, collect EDTA (lavender-top) tube last. Traumatic draw can introduce thromboplastin and trap WBC and platelets. Refrigeration can precipitate fibrin and trap WBC and platelets. Note: If drawn with lead testing, EDTA (tan-top) is required.
Transport container	EDTA (lavender-top) tube
Transport temperature	Room temperature
Specimen stability	Room temperature: 48 hours Refrigerated: 48 hours (may cause platelet clumping) Frozen: Unacceptable
Reject criteria	Gross hemolysis • Clotted • Received frozen

Reflex tests

Test code	Test name	Orderable separately	Reflex criteria
%415	DIFFERENTIAL, MANUAL	No	If abnormal cells are noted on a manual review of the peripheral blood smear, a full manual differential will be performed.
%11018	PLATELET ESTIMATION	No	...
%8562	CBC MORPHOLOGY	No	...
%91341	DIFFERENTIAL, MANUAL	No	If the automated differential information meets specific criteria, a full manual differential will be performed.
%91343	PLATELET ESTIMATION	No	...
%91344	CBC MORPHOLOGY	No	...

Reference range(s)

See Laboratory Report

LOINC® codes

The Result and LOINC® information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table are not orderable Test Codes

Result code	Result name	LOINC code	Component name
30000000	WHITE BLOOD CELL COUNT	6690-2	Leukocytes
30000100	RED BLOOD CELL COUNT	789-8	Erythrocytes
30000200	HEMOGLOBIN	718-7	Hemoglobin
30000300	HEMATOCRIT	4544-3	Erythrocyte/Blood
30000400	MCV	787-2	Observation
30000500	MCH	785-6	Hemoglobin
30000600	MCHC	786-4	Hemoglobin
30000700	RDW	788-0	Erythrocyte
30000800	PLATELET COUNT	777-3	Platelets
30000900	NEUTROPHILS	770-8	Neutrophils/Leukocytes
30001100	BAND NEUTROPHILS	764-1	Neutrophils.band form/Leukocytes
30001110	ABSOLUTE BAND NEUTROPHILS	26507-4	Neutrophils.band form
30001300	METAMYELOCYTES	740-1	Metamyelocytes/Leukocytes
30001310	ABSOLUTE METAMYELOCYTES	30433-7	Metamyelocytes
30001500	MYELOCYTES	749-2	Myelocytes/Leukocytes
30001510	ABSOLUTE MYELOCYTES	30446-9	Myelocytes
30001520	PROMYELOCYTES	783-1	Promyelocytes/Leukocytes
30001530	ABSOLUTE PROMYELOCYTES	26523-1	Promyelocytes
30001700	ABSOLUTE NEUTROPHILS	751-8	Neutrophils
30001800	LYMPHOCYTES	736-9	Lymphocytes/Leukocytes
30002000	REACTIVE LYMPHOCYTES	13046-8	Lymphocytes.variant/Leukocytes
30002110	ABSOLUTE LYMPHOCYTES	731-0	Lymphocytes
30002200	MONOCYTES	5905-5	Monocytes/Leukocytes
30002400	ABSOLUTE MONOCYTES	742-7	Monocytes
30002500	EOSINOPHILS	713-8	Eosinophils/Leukocytes
30002700	ABSOLUTE EOSINOPHILS	711-2	Eosinophils
30002800	BASOPHILS	706-2	Basophils/Leukocytes
30003000	ABSOLUTE BASOPHILS	704-7	Basophils
30003400	BLASTS	709-6	Blasts/Leukocytes
30003500	ABSOLUTE BLASTS	30376-8	Blasts
30003600	NUCLEATED RBC	19048-8	Erythrocytes.nucleated/Leukocytes
30003610	ABSOLUTE NUCLEATED RBC	30392-5	Erythrocytes.nucleated
30004200	COMMENT(S)	8251-1	Service comment
30004600	MPV	776-5	Platelet

DIFFERENTIAL, MANUAL

Result code	Result name	LOINC code	Component name
30000900	NEUTROPHILS	770-8	Neutrophils/Leukocytes
30001100	BAND NEUTROPHILS	764-1	Neutrophils.band form/Leukocytes
30001110	ABSOLUTE BAND NEUTROPHILS	26507-4	Neutrophils.band form
30001300	METAMYELOCYTES	740-1	Metamyelocytes/Leukocytes
30001310	ABSOLUTE METAMYELOCYTES	30433-7	Metamyelocytes
30001500	MYELOCYTES	749-2	Myelocytes/Leukocytes
30001510	ABSOLUTE MYELOCYTES	30446-9	Myelocytes
30001520	PROMYELOCYTES	783-1	Promyelocytes/Leukocytes
30001530	ABSOLUTE PROMYELOCYTES	26523-1	Promyelocytes
30001700	ABSOLUTE NEUTROPHILS	751-8	Neutrophils
30001800	LYMPHOCYTES	736-9	Lymphocytes/Leukocytes
30002000	REACTIVE LYMPHOCYTES	13046-8	Lymphocytes.variant/Leukocytes
30002010	ABSOLUTE REACTIVE LYMPHOCYTES	734-4	Lymphocytes.variant
30002120	ABSOLUTE LYMPHOCYTES	732-8	Lymphocytes
30002200	MONOCYTES	5905-5	Monocytes/Leukocytes
30002400	ABSOLUTE MONOCYTES	742-7	Monocytes
30002500	EOSINOPHILS	713-8	Eosinophils/Leukocytes
30002700	ABSOLUTE EOSINOPHILS	711-2	Eosinophils
30002800	BASOPHILS	706-2	Basophils/Leukocytes
30003000	ABSOLUTE BASOPHILS	704-7	Basophils
30003400	BLASTS	709-6	Blasts/Leukocytes
30003500	ABSOLUTE BLASTS	30376-8	Blasts
30003600	NUCLEATED RBC	19048-8	Erythrocytes.nucleated/Leukocytes
30003610	ABSOLUTE NUCLEATED RBC	30392-5	Erythrocytes.nucleated
30003640	PLATELET ESTIMATION	9317-9	Platelets
30003650	CBC MORPHOLOGY	18314-5	Morphology
30004200	COMMENT(S)	8251-1	Service comment
30004240	NOTE		Pending assignment
30004250	ABSOLUTE PROLYMPHOCYTES	6863-5	Prolymphocytes
30004260	ABSOLUTE PLASMA CELLS	24103-4	Plasma cells
30004270	PROLYMPHOCYTES	6746-2	Prolymphocytes/Leukocytes
30004280	PLASMA CELLS	13047-6	Plasma cells/Leukocytes

PLATELET ESTIMATION

Result code	Result name	LOINC code	Component name
30003640	PLATELET ESTIMATION	9317-9	Platelets

CBC MORPHOLOGY

Result code	Result name	LOINC code	Component name
30003650	CBC MORPHOLOGY	18314-5	Morphology

DIFFERENTIAL, MANUAL

Result code	Result name	LOINC code	Component name
30000900	NEUTROPHILS	770-8	Neutrophils/Leukocytes
30001100	BAND NEUTROPHILS	764-1	Neutrophils.band form/Leukocytes
30001110	ABSOLUTE BAND NEUTROPHILS	26507-4	Neutrophils.band form
30001300	METAMYELOCYTES	740-1	Metamyelocytes/Leukocytes
30001310	ABSOLUTE METAMYELOCYTES	30433-7	Metamyelocytes
30001500	MYELOCYTES	749-2	Myelocytes/Leukocytes
30001510	ABSOLUTE MYELOCYTES	30446-9	Myelocytes
30001520	PROMYELOCYTES	783-1	Promyelocytes/Leukocytes
30001530	ABSOLUTE PROMYELOCYTES	26523-1	Promyelocytes
30001700	ABSOLUTE NEUTROPHILS	751-8	Neutrophils
30001800	LYMPHOCYTES	736-9	Lymphocytes/Leukocytes
30002000	REACTIVE LYMPHOCYTES	13046-8	Lymphocytes.variant/Leukocytes
30002010	ABSOLUTE REACTIVE LYMPHOCYTES	734-4	Lymphocytes.variant
30002120	ABSOLUTE LYMPHOCYTES	732-8	Lymphocytes
30002200	MONOCYTES	5905-5	Monocytes/Leukocytes
30002400	ABSOLUTE MONOCYTES	742-7	Monocytes
30002500	EOSINOPHILS	713-8	Eosinophils/Leukocytes
30002700	ABSOLUTE EOSINOPHILS	711-2	Eosinophils
30002800	BASOPHILS	706-2	Basophils/Leukocytes
30003000	ABSOLUTE BASOPHILS	704-7	Basophils
30003400	BLASTS	709-6	Blasts/Leukocytes
30003500	ABSOLUTE BLASTS	30376-8	Blasts
30003600	NUCLEATED RBC	19048-8	Erythrocytes.nucleated/Leukocytes
30003610	ABSOLUTE NUCLEATED RBC	30392-5	Erythrocytes.nucleated
30003640	PLATELET ESTIMATION	9317-9	Platelets
30003650	CBC MORPHOLOGY	18314-5	Morphology
30004200	COMMENT(S)	8251-1	Service comment
30004240	NOTE		Pending assignment
30004250	ABSOLUTE PROLYMPHOCYTES	6863-5	Prolymphocytes
30004260	ABSOLUTE PLASMA CELLS	24103-4	Plasma cells
30004270	PROLYMPHOCYTES	6746-2	Prolymphocytes/Leukocytes
30004280	PLASMA CELLS	13047-6	Plasma cells/Leukocytes

PLATELET ESTIMATION

Result code	Result name	LOINC code	Component name
30003640	PLATELET ESTIMATION	9317-9	Platelets

CBC MORPHOLOGY

Result code	Result name	LOINC code	Component name
30003650	CBC MORPHOLOGY	18314-5	Morphology

Performing lab & setup schedule

Performing laboratory

Quest Diagnostics - East Region

Setup schedule

Set up: Daily (All shifts); Report available: 3 days

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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