Lithium
Test Code
613
80178
Clinical Significance
Lithium - Lithium is used to treat manic-depressive disorders and the manic phase of affective disorders, including mania. The therapeutic window is relatively small. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity.
Test Resources
Test Details
Collect just prior to next dose
Methodology
Immunoassay (IA) • Inductively Coupled Plasma/Mass Spectrometry (ICP/MS) • Spectrometry • Spectrophotometry (SP)
Reference Range(s)
0.6-1.2 mmol/L
Preferred Specimen(s)
2 mL serum
Alternative Specimen(s)
Serum separator (gel barrier) tubes • EDTA plasma • No lithium containing anticoagulants
Minimum Volume
0.5 mL
Transport Container
Serum separator tube (SST)
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 10 days
- Refrigerated: 10 days
- Frozen: Not established
Reject Criteria
Plasma from lithium-based anticoagulants
Setup Schedule
2 mL serum
Serum separator (gel barrier) tubes • EDTA plasma • No lithium containing anticoagulants
0.5 mL
Serum separator tube (SST)
Room temperature
Room temperature: 10 days
Refrigerated: 10 days
Frozen: Not established
Refrigerated: 10 days
Frozen: Not established
Plasma from lithium-based anticoagulants