Lactic Acid, Plasma
Test Code
Clinical Significance
Lactic Acid, Plasma - Lactic acid is the endproduct of the anaerobic metabolism of glucose. The blood lactic acid concentration is affected by its production in muscle cells and erythrocytes and its rate of metabolism in the liver. During exercise, blood lactate can increase up to ten times of normal levels.
Test Resources
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Test Details
Methodology
Reference Range(s)
Preferred Specimen(s)
2 mL frozen plasma from a gray-top tube
Minimum Volume
0.5 mL
Collection Instructions
The collected blood should be well-mixed and separated from the cells within 3 hours. Freeze plasma and ship frozen.
The assay manufacturer, Roche, notes that N-acetylcysteine, when administered in high concentrations (such as for treatment of acetaminophen overdose), can interfere with their assay for Lactate (Lactic Acid), leading to falsely low results.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 72 hours
- Frozen: 30 days
Reject Criteria
Gross hemolysis • Grossly lipemic • Grossly icteric
Setup Schedule
2 mL frozen plasma from a gray-top tube
The assay manufacturer, Roche, notes that N-acetylcysteine, when administered in high concentrations (such as for treatment of acetaminophen overdose), can interfere with their assay for Lactate (Lactic Acid), leading to falsely low results.
Refrigerated: 72 hours
Frozen: 30 days