Complement Component C3c and C4c
Test Code
5704
86160 (x2)
Clinical Significance
Complement Component C3c and C4c - Decreased concentrations of both C3 and C4 suggest activation of the classical pathway, whereas decreased concentration of just C3 suggests activation of the alternative pathway. Both complement factors may be used to monitor activity of patients with systemic lupus erythematosus (SLE) and immune complex-induced vasculitis.
Test Resources
None found for this test
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Test Details
Methodology
Immunoturbidimetric
Reference Range(s)
See individual tests
Alternative Name(s)
C3 & C4 Complements,C4 & C3 Complements
Preferred Specimen(s)
1 mL serum
Minimum Volume
0.5 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: Unacceptable
Refrigerated: 8 days
Frozen: 8 days
Setup Schedule, Reject Criteria
1 mL serum
0.5 mL
Transport tube
Refrigerated (cold packs)
Room temperature: Unacceptable
Refrigerated: 8 days
Frozen: 8 days
Refrigerated: 8 days
Frozen: 8 days